Research Article
Pharmacokinetics of 10-Hydroxy Mesaconitine in Rat Plasma by Ultra-Performance Liquid Chromatography-Tandem Quadrupole Mass Spectrometry
Table 2
Summary of the stability of 10-hydroxy mesaconitine under various storage conditions (n = 3).
| Concentration (ng/mL) | Autosampler (4°C, 12 h) | Ambient (2 h) | –20°C (30 d) | Freeze-thaw | Accuracy (%) | RSD (%) | Accuracy (%) | RSD (%) | Accuracy (%) | RSD (%) | Accuracy (%) | RSD (%) |
| 0.8 | 97.2 | 1.8 | 102.9 | 8.0 | 112.7 | 9.0 | 89.9 | 12.4 | 12 | 97.5 | 6.7 | 109.1 | 6.0 | 95.6 | 9.7 | 101.4 | 8.9 | 50 | 103.0 | 0.5 | 94.5 | 2.1 | 97.0 | 10.4 | 86.7 | 10.6 |
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