Research Article
Graphene Oxide-Gold Star Construct on Triangular Electrodes for Alzheimer’s Disease Identification
Table 1
Comparison among the available methods for Alzheimer’s disease identification.
| Method | Target | Selectivity | Sensitivity | Advantage | Reference |
| Electrochemical sensor | MicroRNA | 5–750 fM | 1.7 fM | Gold-graphene improves detection | [22] | Immunomagnetic biosensor | Aβ42 | 5–800 pg/mL | 5 pg/mL | Cheaper with shorten time | [29] | Electrochemical sensor | Aβ1–42 | 0.011–55 nM | 2.398 pM | Graphene-rGO improves detection | [30] | Immunoelectrochemical sensor | Aβ | 0.14–1 ng/mL | 0.14 ng/mL | Biocompatible fabrication | [31] | SPR | Acetylcholine | 0–10 μM | 38 nM | Remote sensing and compactness | [32] | Multiplex aptasensor | Aβ42 | 0–1000 fM | 8.4 fM | Simultaneous detection | [33] | Multiplex aptasensor | Tau-441 | 0–1000 fM | 4.3 fM | Simultaneous detection | [33] | Interdigitated electrode | miRNA-137 | 1 fM–10 pM | 1 fM | Negligible biofouling and improved detection | This work |
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