A Fast and Validated HPLC Method for Simultaneous Determination of Dopamine, Dobutamine, Phentolamine, Furosemide, and Aminophylline in Infusion Samples and Injection Formulations

Table 4

The robustness of the proposed HPLC method.

Parameter	Variable	Recovery (%)
		DPM	DBM	PTM	FSM	APL
Flow rate (mL·min^−1)	0.9	97.8	98.8	98.4	99.9	98.9
	1.0	97.5	100.6	101.3	98.7	98.4
	1.1	100.3	98.1	98.5	100.1	99.7
	29	99.5	99.1	100.2	99.4	98.8
Column temperature (°C)	30	99.6	98.9	99.7	98.6	99
	31	98.8	99.2	99.7	100.5	99.4
	48	99.2	99.9	97.9	99.6	101.3
Buffer concentration (mM)	50	100.9	98.6	101.6	100.7	98.6
	52	98.7	98.3	98.3	98.9	100.5
Mean		99.1	99.1	99.5	99.6	99.4
%RSD		1.1	0.8	1.3	0.8	1.0