A Joint Technology Combining the Advantages of Capillary Microsampling with Mass Spectrometry Applied to the Trans-Resveratrol Pharmacokinetic Study in Mice
Table 3
Matrix effect and recovery of trans-resveratrol, R3G, R3S, and diethylstilbestrol (IS).
Analytes
Matrix effect
Recovery (%)
LQC
HQC
LQC
MQC
HQC
Trans-resveratrol
103.37 ± 14.08 (13.62)
88.32 ± 4.75 (5.38)
83.82 ± 8.12 (9.69)
79.97 ± 4.30 (5.38)
79.66 ± 2.10 (2.64)
R3G
105.32 ± 12.82 (12.17)
100.30 ± 4.46 (4.45)
89.28 ± 6.42 (7.20)
83.54 ± 8.38 (10.03)
83.38 ± 2.04 (2.45)
R3S
97.95 ± 2.90 (2.96)
95.36 ± 2.95 (3.10)
89.46 ± 5.21 (5.82)
89.52 ± 1.52 (1.70)
85.19 ± 2.98 (3.49)
Diethylstilbestrol
96.41 ± 10.09 (10.46)
99.94 ± 4.78 (4.78)
Data are represented as mean ± SD (RSD%). R3G, trans-resveratrol-3-o-β-glucuronide; R3S, trans-resveratrol-3-sulfate salt.
