Table of Contents
Journal of Anesthesiology
Volume 2015, Article ID 619860, 5 pages
Clinical Study

The Effects of Intrathecal Fentanyl on Sedation Depth and Postoperative Recovery Room Delirium

1Department of Anesthesiology and Reanimation, Sureyyapasa Pulmonary Disease Hospital, Istanbul, Turkey
2Department of Anesthesiology and Reanimation, Umraniye Research and Education Hospital, Istanbul, Turkey
3Department of Anesthesiology and Reanimation, Afsin Government Hospital, Afsin, Turkey

Received 21 August 2015; Accepted 5 November 2015

Academic Editor: Robert J. Brosnan

Copyright © 2015 Ozgur Bulent Tuzun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background/Aim. Intrathecal anaesthesia has been shown to increase sedation level. This study aimed to evaluate the effects of intrathecal applied fentanyl with levobupivacaine on intraoperative sedation and recovery room delirium. Materials and Methods. The study included 68 patients, ASA I–III, 55–85 years. One day preoperatively, the Confusion Assessment Method (CAM) and the Mini Mental Status Test (MMST) were applied and patients were separated into two groups. In Group L 2.5 mL levobupivacaine and in Group LF 2 mL levobupivacaine and 0.5 mL fentanyl were applied intrathecally. In a supine position, following a propofol IV 1 mg kg−1 bolus to obtain Bispectral Index (BIS) of 70–85, propofol infusion was started (1 mg kg−1 st−1). With observation of SpO2, BIS, and the Observer Assessment and Alertness/Sedation Scale (OAA/SS) with the haemodynamic values, the total propofol amount was calculated. Evaluations were made of pain severity (VAS), analgesic use, transfusion requirement, and recovery room delirium. Results. In the comparison within the groups, a significant decrease was determined in HR and MAP compared to the initial values (). A positive correlation was found between the BIS and OAA/SS values. The amounts of propofol used were similar between the groups. Conclusions. Intrathecal fentanyl and levobupivacaine had the same effect on sedation or BIS and fentanyl did not cause delirium.