Self-Renewal Signalling in Presenescent Tetraploid IMR90 Cells
Figure 10
Relatively rare flattening giant fibroblasts displaying at presenescence a considerable accumulation of NANOG filling the whole nucleus in parallel to clear DAPI-positive SAHFs; in addition, the cells contain p16-positive material in the cytoplasm. Images were obtained using BRG three-colour optical filters system. Scale bars = 10 μm.