Research Article

Self-Renewal Signalling in Presenescent Tetraploid IMR90 Cells

Figure 2

Histograms of IMR90 DNA content in several passages showing typical changes in the time course: (a) logarithmic growth, (b) presenescence, (c) late presenescence, and (d) senescence showing the accumulation of 4C cells and the increase of the proportion of hypertetraploid cells, some of which reach octoploidy.
103253.fig.002a
(a)
103253.fig.002b
(b)
103253.fig.002c
(c)
103253.fig.002d
(d)