Self-Renewal Signalling in Presenescent Tetraploid IMR90 Cells
Figure 2
Histograms of IMR90 DNA content in several passages showing typical changes in the time course: (a) logarithmic growth, (b) presenescence, (c) late presenescence, and (d) senescence showing the accumulation of 4C cells and the increase of the proportion of hypertetraploid cells, some of which reach octoploidy.