Self-Renewal Signalling in Presenescent Tetraploid IMR90 Cells
Figure 4
Tetraploidy increases in the course of IMR90 senescence. (a) The number of hypertetraploid cells increases with senescence and strongly inversely correlates with mitotic indices in each experimental series; (b) the number of cells with octoploid DNA content increases with hypertetraploidy indicating to increase of tetraploid cycling (the united data from three experiments).