Striatal Hypodensities, Not White Matter Hypodensities on CT, Are Associated with Late-Onset Depression in Alzheimer's Disease

Table 5

risk of subcortical white matter hypodensities in late-onset depression compared with no depression for all dementia and Alzheimer’s disease only.

	No depression				Late-onset depression
Level of WMH*	0	1	2	3	0	1	2	3	OR (95% CI)**
All dementia	62 (47.0)	16 (12.1)	25 (18.9)	29 (22.0)	17 (47.2)	3 (8.33)	9 (25.0)	7 (19.4)	0.97 (0.48, 1.92)
AD only	48 (50.5)	11 (11.6)	18 (18.9)	18 (18.9)	12 (48.0)	2 (8.0)	5 (20.0)	6 (24.0)	1.16 (0.48, 2.58)

OR: ordinal cumulative logit odds ratio estimate, controlling for age at time of CT scan; CI: confidence interval; AD: Alzheimer’s disease.
Level of WMH: 0 = none, 1 = one discrete hypodensity, 2 = more than one discrete hypodensity, 3 = confluent hypodensities.
*All numbers for Level of WMH given in terms of 𝑁 (%). **Late-onset depression group compared to no depression group.