Clinical Study

Cognitive Stimulation for Apathy in Probable Early-Stage Alzheimer's

Table 1

Participant demographics (values are presented as (%) or mean (standard deviation)).

TotalControl (social support)Treatment (mentally stimulating activities) value

Participants ( ) 7729*48
Gender.243
 Male15 (19.5%)4 (13.8%)11 (22.9%)
 Female62 (80.5%)25 (86.2%)36 (77.1%)
Race.071
 Caucasian56 (72.7%)17 (58.6%)39 (81.3%)
 African-American20 (25.9%)11 (37.9%)9 (18.7%)
 Hispanic1 (1.3%)1 (.03%)0 (0%)
Depression DX.594
 Yes207 (24.1%)13 (27.1%)
 No5722 (75.9%)35 (72.9%)
Mean Age82.2 (6.5)81.0 (8.7).07
Years of Education13.6 (3.8)14.6 (3.6).499
Baselines
 MMSE25.4 (2.8)25.2 (3.3).269
 AES (Apathy)30.4 (7.9)32.8 (8.7).331
 Cornell-Brown18.6 (11.3)14.3 (10.8).758
 PHQ-94.7 (4.8)5.9 (5.7).188
 Trail Making Time192.80 (89.7)178.45 (90.0).635

*48 participants were enrolled but 19 dropped after baseline recruitment and evaluation due to health problems and lack of interest in the intervention (39%). These participants were not included in the pre-post analysis.