Estradiol Modulates Membrane-Linked ATPases, Antioxidant Enzymes, Membrane Fluidity, Lipid Peroxidation, and Lipofuscin in Aged Rat Liver

Table 2

Changes in polarization and anisotropy measurements in liver of 3, 12, and 24 months of control (C) and estradiol- (E2-) treated aging female rats.

Age/treatment	Membrane fluidity
	Polarization (𝑃)	Anisotropy (𝑟)
3 months
C	0.170±0.002	0.157±0.002
12 months
C	0.208±0.003^$	0.195±0.003^$
E2	0.195±0.002^#	0.172±0.004^b
24 months
C	0.224±0.008^$	0.203±0.005^$
E2	0.179±0.002^a	0.161±0.008^a

Each value is a mean ± SEM of five or more separate values from two to three experiments. The comparisons of experimental values are with the control values. Statistical significance: ^a𝑃<0.001,^b𝑃<0.01 comparing age matched controls versus E2 treatment and ^$𝑃<0.001, ^#𝑃<0.01 versus 3 months.