Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men
Table 3
Hazard ratios of CVD mortality by alcohol consumption level in men, Aerobics Center for Longitudinal Study (ACLS), 1974–2002.
Alcohol consumption (drinks/week)
Nondrinkers (0)
Quartile 1 (1–3)
Quartile 2 (4–6)
Quartile 3 (7–13)
Quartile 4 (≥14)
Person-years
86,872
91,529
98,303
103,625
124,360
No.
4742
6663
6049
6735
6860
No. of Deaths
128
70
101
106
183
Death ratea
17.0
11.6
13.1
12.9
17.7
Basic modelb
1.00 (referent)
0.71 (0.53–0.95)
0.75 (0.58–0.98)
0.83 (0.64–1.08)
1.00 (0.80–1.26)
Basic model plus
Blood pressure factorsc
1.00 (referent)
0.70 (0.53–0.94)
0.73 (0.56–0.95)
0.84 (0.64–1.09)
0.94 (0.75–1.18)
Fasting glucose factorsd
1.00 (referent)
0.68 (0.51–0.91)
0.75 (0.58–0.98)
0.82 (0.63–1.07)
0.98 (0.78–1.24)
Lipid factorse
1.00 (referent)
0.71 (0.53–0.95)
0.73 (0.56–0.96)
0.80 (0.62–1.04)
0.95 (0.75–1.19)
All intermediate factorscde
1.00 (referent)
0.68 (0.51–0.91)
0.71 (0.55–0.93)
0.81 (0.62–1.05)
0.88 (0.69–1.11)
aDeath rate per 10,000 person-years adjusted for age (in years).
bAdjusted for age (in years), year of examination, BMI (kg/m2), smoking (current smoker or not), family history of CVD (yes or no), and maximal treadmill time (min).
cSystolic blood pressure and reported hypertension (yes or no).
dFasting glucose and reported diabetes (yes or no).
eTotal cholesterol and triglyceride.