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Journal of Aging Research
Volume 2011, Article ID 903291, 8 pages
Review Article

Intervening on the Side Effects of Hormone-Dependent Cancer Treatment: The Role of Strength Training

Department of Kinesiology, School of Public Health, University of Maryland, College Park, MD 20742, USA

Received 1 October 2010; Accepted 15 December 2010

Academic Editor: Iris Reuter

Copyright © 2011 Erik D. Hanson and Ben F. Hurley. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


While prostate and breast cancers are both highly prevalent and treatable using hormone suppression therapy, a constellation of side effects ensue, which mimic typical aging effects but at an accelerated pace. Because strength training is considered to be an intervention of choice for addressing the musculoskeletal and metabolic consequences of normal aging in older adults, it may be an effective intervention to attenuate or reverse the side effects of hormone-dependent cancer treatment. This paper provides an overview of the independent effects of strength training on common musculoskeletal and metabolic side effects of hormone-dependent therapy used for prostate and breast cancers. Strength training appears to be an effective complementary therapy for some of the adverse effects of prostate and breast treatment. Future research needs to address potential mechanisms to explain recent findings and to explore the role of strength training in addressing specific risk factors resulting from cancer treatment.