Journal of Aging Research / 2011 / Article / Fig 3

Review Article

Proteomic Profiling of Mitochondrial Enzymes during Skeletal Muscle Aging

Figure 3

Proteomic profiling of the mitochondria-enriched fraction from aged skeletal muscle tissue. Shown is the comparative graphic representation of distinct two-dimensional protein spots with a changed expression in aged muscle as judged by fluorescence difference in-gel electrophoretic analysis [97]. Individual panels document alterations in the abundance of NADH dehydrogenase (NADH-DH), the inner mitochondrial membrane protein mitofilin, prohibitin, the porin isoform VDAC 2, succinate dehydrogenase (SDH), acyl-coenzyme A dehydrogenase (Acyl-CoA-DH), peroxiredoxin isoform PRX-III, ubiquinol-cytochrome c reductase core I protein (Ubq-Cytc-RED), succinate-coenzyme A (Suc-CoA) ligase, and mitochondrial F1-ATPase.

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