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Journal of Aging Research
Volume 2012, Article ID 235765, 15 pages
http://dx.doi.org/10.1155/2012/235765
Clinical Study

Efficacy of a Multimodal Cognitive Rehabilitation Including Psychomotor and Endurance Training in Parkinson's Disease

1Department of Neurology, Justus-Liebig University, Klinikstraße 33, 35392 Giessen, Germany
2Department of Psychiatry, Cognitive Laboratory Justus-Liebig University, Am Steg 22, 35385 Giessen, Germany
3Neurologisches Rehabilitationszentrum, HELIOS Klinik Zihlschlacht AG, Hauptstrße 2-4, 8588 Zihlschlacht, Switzerland
4Department of Orthopedic Surgery, Klinikum Osnabrück, Am Finkenhügel 1, 49076 Osnabrück, Germany

Received 1 April 2012; Revised 19 June 2012; Accepted 3 July 2012

Academic Editor: Alice Nieuwboer

Copyright © 2012 I. Reuter et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. C. Chen, S. F. Chang, C. L. Su et al., “Prevalence, incidence, and mortality of PD: a door-to-door survey in Ilan County, Taiwan,” Neurology, vol. 57, no. 9, pp. 1679–1686, 2001. View at Google Scholar · View at Scopus
  2. A. Schrag, Y. Ben-Shlomo, and N. P. Quinn, “Cross sectional prevalence survey of idiopathic Parkinson's disease and parkinsonism in London,” British Medical Journal, vol. 321, no. 7252, pp. 21–22, 2000. View at Google Scholar · View at Scopus
  3. J. Douglas, D. J. Gelb, E. Oliver, and S. Gilman, “Diagnostic criteria for Parkinson disease,” Archives of Neurology, vol. 56, no. 1, pp. 33–39, 1999. View at Publisher · View at Google Scholar · View at Scopus
  4. A. J. Hughes, S. E. Daniel, L. Kilford, and A. J. Lees, “Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases,” Journal of Neurology Neurosurgery and Psychiatry, vol. 55, no. 3, pp. 181–184, 1992. View at Google Scholar · View at Scopus
  5. D. Aarsland, K. Andersen, J. P. Larsen, A. Lolk, and P. Kragh-Sørensen, “Prevalence and characteristics of dementia in Parkinson disease: an 8-year prospective study,” Archives of Neurology, vol. 60, no. 3, pp. 387–392, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. M. Emre, D. Aarsland, A. Albanese et al., “Rivastigmine for dementia associated with Parkinson's disease,” New England Journal of Medicine, vol. 351, no. 24, pp. 2509–2518, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. G. Levy, M. X. Tang, E. D. Louis et al., “The association of incident dementia with mortality in PD,” Neurology, vol. 59, no. 11, pp. 1708–1713, 2002. View at Google Scholar · View at Scopus
  8. A. Schrag, M. Jahanshahi, and N. Quinn, “What contributes to quality of life in patients with Parkinson's disease?” Journal of Neurology Neurosurgery and Psychiatry, vol. 69, no. 3, pp. 308–312, 2000. View at Publisher · View at Google Scholar · View at Scopus
  9. D. Aarsland, J. P. Larsen, K. Karlsen, N. G. Lim, and E. Tandberg, “Mental symptoms in Parkinson's disease are important contributors to caregiver distress,” International Journal of Geriatric Psychiatry, vol. 14, no. 10, pp. 866–874, 1999. View at Publisher · View at Google Scholar
  10. D. Aarsland, J. P. Larsen, E. Tandberg, and K. Laake, “Predictors of nursing home placement in Parkinson's disease: a population-based, prospective study,” Journal of the American Geriatrics Society, vol. 48, no. 8, pp. 938–942, 2000. View at Google Scholar · View at Scopus
  11. M. Emre, “Dementia associated with Parkinson's disease,” Lancet Neurology, vol. 2, no. 4, pp. 229–237, 2003. View at Publisher · View at Google Scholar · View at Scopus
  12. H. Braak, K. Del Tredici, U. Rüb, R. A. I. De Vos, E. N. H. Jansen Steur, and E. Braak, “Staging of brain pathology related to sporadic Parkinson's disease,” Neurobiology of Aging, vol. 24, no. 2, pp. 197–211, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. E. K. Perry, M. Curtis, and D. J. Dick, “Cholinergic correlates of cognitive impairment in Parkinson's disease: comparisons with Alzheimer's disease,” Journal of Neurology Neurosurgery and Psychiatry, vol. 48, no. 5, pp. 413–421, 1985. View at Google Scholar · View at Scopus
  14. I. Litvan, D. Aarsland, C. H. Adler et al., “MDS task force on mild cognitive impairment in Parkinson's disease: critical review of PD-MCI,” Movement Disorders, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. E. E. Smith and J. Jonides, “Storage and executive processes in the frontal lobes,” Science, vol. 283, no. 5408, pp. 1657–1661, 1999. View at Publisher · View at Google Scholar · View at Scopus
  16. P. W. Burgess and T. Shallice, “Response suppression, initiation and strategy use following frontal lobe lesions,” Neuropsychologia, vol. 34, no. 4, pp. 263–272, 1996. View at Publisher · View at Google Scholar · View at Scopus
  17. E. K. Miller and J. D. Cohen, “An integrative theory of prefrontal cortex function,” Annual Review of Neuroscience, vol. 24, pp. 167–202, 2001. View at Publisher · View at Google Scholar · View at Scopus
  18. R. D. Abbott, L. R. White, G. W. Ross, K. H. Masaki, J. D. Curb, and H. Petrovitch, “Walking and dementia in physically capable elderly men,” Journal of the American Medical Association, vol. 292, no. 12, pp. 1447–1453, 2004. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Colcombe and A. F. Kramer, “Fitness effects on the cognitive function of older adults: a meta-analytic study,” Psychological Science, vol. 14, no. 2, pp. 125–130, 2003. View at Publisher · View at Google Scholar · View at Scopus
  20. S. J. Colcombe, K. I. Erickson, N. Raz et al., “Aerobic fitness reduces brain tissue loss in aging humans,” Journals of Gerontology A, vol. 58, no. 2, pp. 176–180, 2003. View at Google Scholar
  21. S. J. Colcombe, K. I. Erickson, P. E. Scalf et al., “Aerobic exercise training increases brain volume in aging humans,” Journals of Gerontology A, vol. 61, no. 11, pp. 1166–1170, 2006. View at Google Scholar · View at Scopus
  22. D. Laurin, R. Verreault, J. Lindsay, K. MacPherson, and K. Rockwood, “Physical activity and risk of cognitive impairment and dementia in elderly persons,” Archives of Neurology, vol. 58, no. 3, pp. 498–504, 2001. View at Google Scholar · View at Scopus
  23. Y. Rolland, G. Abellan van Kan, and B. Vellas, “Healthy brain aging: role of exercise and physical activity,” Clinics in Geriatric Medicine, vol. 26, no. 1, pp. 75–87, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. G. Nelles, “Cortical reorganization—effects of intensive therapy: results from prospective functional imaging studies,” Restorative Neurology and Neuroscience, vol. 22, no. 3-4, pp. 239–244, 2004. View at Google Scholar · View at Scopus
  25. R. B. Shepherd, “Exercise and training to optimize functional motor performance in stroke: driving neural reorganization?” Neural Plasticity, vol. 8, no. 1-2, pp. 121–129, 2001. View at Google Scholar · View at Scopus
  26. A. F. Kramer, S. Hahn, N. J. Cohen et al., “Ageing, fitness and neurocognitive function,” Nature, vol. 400, no. 6743, pp. 418–419, 1999. View at Publisher · View at Google Scholar · View at Scopus
  27. J. Baatile, W. E. Langbein, F. Weaver, C. Maloney, and M. B. Jost, “Effect of exercise on perceived quality of life of individuals with Parkinson's disease,” Journal of Rehabilitation Research and Development, vol. 37, no. 5, pp. 529–534, 2000. View at Google Scholar · View at Scopus
  28. I. Reuter, M. Engelhardt, K. Stecker, and H. Baas, “Therapeutic value of exercise training in Parkinson's disease,” Medicine and Science in Sports and Exercise, vol. 31, no. 11, pp. 1544–1549, 1999. View at Google Scholar · View at Scopus
  29. K. Dujardin, A. Duhamel, M. Delliaux, C. Thomas-Antérion, A. Destée, and L. Defebvre, “Cognitive complaints in Parkinson's disease: its relationship with objective cognitive decline,” Journal of Neurology, vol. 257, no. 1, pp. 79–84, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. S. Fahn, R. L. Elton, and The Members of the UPDRS Development Committee, “Unified Parkinson's disease rating scale,” in Recent Developments in Parkinson's Disease II, S. Fahn, C. D. Marsden, M. Goldstein et al., Eds., pp. 153–163, McMillan, New York, NY, USA, 1987. View at Google Scholar
  31. Royal College of Physicians and the Intercollegiate Stroke Working Party, National Clinical Guideline for Stroke, RCP, London, UK, 3rd edition, 2008.
  32. E. Kalbe, P. Calabrese, N. Kohn et al., “Screening for cognitive deficits in Parkinson's disease with the Parkinson neuropsychometric dementia assessment (PANDA) instrument,” Parkinsonism and Related Disorders, vol. 14, no. 2, pp. 93–101, 2008. View at Publisher · View at Google Scholar · View at Scopus
  33. M. F. Folstein, S. E. Folstein, and P. R. McHugh, “'Mini mental state'. A practical method for grading the cognitive state of patients for the clinician,” Journal of Psychiatric Research, vol. 12, no. 3, pp. 189–198, 1975. View at Publisher · View at Google Scholar · View at Scopus
  34. W. G. Rosen, R. C. Mohs, and K. L. Davis, “A new rating scale for Alzheimer's disease,” American Journal of Psychiatry, vol. 141, no. 11, pp. 1356–1364, 1984. View at Google Scholar · View at Scopus
  35. S. Talwalker, “Assessment of AD with the ADAS-cog,” Journal of Geriatric Psychiatry and Neurology, vol. 9, pp. 39–46, 1996. View at Google Scholar
  36. J. Marinus, M. Visser, N. A. Verwey et al., “Assessment of cognition in Parkinson's disease,” Neurology, vol. 61, no. 9, pp. 1222–1228, 2003. View at Google Scholar · View at Scopus
  37. D. M. A. Gronwall, “Paced auditory serial addition task: a measure of recovery from concussion,” Perceptual and Motor Skills, vol. 44, no. 2, pp. 367–373, 1977. View at Google Scholar · View at Scopus
  38. B. A. Wilson, J. J. Evans, H. Emslie, N. Alderman, and P. Burgess, “The development of an ecologically valid test for assessing patients with a dysexecutive syndrome,” Neuropsychological Rehabilitation, vol. 8, no. 3, pp. 213–228, 1998. View at Google Scholar · View at Scopus
  39. S. Lehrl, Mehrfach-Wortschatz-Intelligenztest: MWT-B, Perimed Fachbuch-Verlagsgesellschaft mbH, Erlangen, Germany, 1989.
  40. A. S. Zigmond and R. P. Snaith, “The hospital anxiety and depression scale,” Acta Psychiatrica Scandinavica, vol. 67, no. 6, pp. 361–370, 1983. View at Google Scholar · View at Scopus
  41. C. Jenkinson, V. Peto, R. Fitzpatrick, R. Greenhall, and N. Hyman, “Self-reported functioning and well-being in patients with Parkinson's disease: comparison of the short-form wealth survey (SF-36) and the Parkinson's disease questionnaire (PDQ-39),” Age and Ageing, vol. 24, no. 6, pp. 505–509, 1995. View at Google Scholar · View at Scopus
  42. S. J. G. Lewis, A. Slabosz, T. W. Robbins, R. A. Barker, and A. M. Owen, “Dopaminergic basis for deficits in working memory but not attentional set-shifting in Parkinson's disease,” Neuropsychologia, vol. 43, no. 6, pp. 823–832, 2005. View at Publisher · View at Google Scholar · View at Scopus
  43. N. Fournet, O. Moreaud, J. L. Roulin, B. Naegele, and J. Pellat, “Working memory functioning in medicated Parkinson's disease patients and the effect of withdrawal of dopaminergic medication,” Neuropsychology, vol. 14, no. 2, pp. 247–253, 2000. View at Publisher · View at Google Scholar · View at Scopus
  44. S. Golubović, T. Tubić, and S. Marković, “Psycho-motor re-education-movement as therapeutic method,” Medicinski Pregled, vol. 64, no. 1-2, pp. 61–63, 2011. View at Google Scholar
  45. T. Golubović, J. Maksimović, B. Golubović, and N. Glumbić, “Effects of exercise on physical fitness in children with intellectual disability,” Research in Developmental Disabilities, vol. 33, no. 2, pp. 608–614, 2012. View at Publisher · View at Google Scholar
  46. W. D. Oswald, R. Rupprecht, T. Gunzelmann, and K. Tritt, “The SIMA-project: effects of 1 year cognitive and psychomotor training on cognitive abilities of the elderly,” Behavioural Brain Research, vol. 78, no. 1, pp. 67–72, 1996. View at Publisher · View at Google Scholar · View at Scopus
  47. W. D. Oswald, T. Gunzelmann, R. Rupprecht, and B. Hagen, “Differential effects of single versus combined cognitive and physical training with older adults: the SimA study in a 5-year perspective,” European Journal of Ageing, vol. 3, no. 4, pp. 179–192, 2006. View at Publisher · View at Google Scholar · View at Scopus
  48. S. Goebel, H. M. Mehdorn, and B. Leplow, “Strategy instruction in Parkinson's disease: influence on cognitive performance,” Neuropsychologia, vol. 48, no. 2, pp. 574–580, 2010. View at Publisher · View at Google Scholar · View at Scopus
  49. A. D. Baddeley, Working Memory, Clarendon Press, Oxford, UK, 1986.
  50. D. A. Norman and T. Shallice, “(1980) Attention to action: willed and automatic control of behaviour,” in Cognitive Neuroscience A, M. S. Gazzaniga, Ed., Blackwell, Oxford, UK, 2000. View at Google Scholar
  51. G. Sammer, I. Reuter, K. Hullmann, M. Kaps, and D. Vaitl, “Training of executive functions in Parkinson's disease,” Journal of the Neurological Sciences, vol. 248, no. 1-2, pp. 115–119, 2006. View at Publisher · View at Google Scholar · View at Scopus
  52. J. D. Churchill, R. Galvez, S. Colcombe, R. A. Swain, A. F. Kramer, and W. T. Greenough, “Exercise, experience and the aging brain,” Neurobiology of Aging, vol. 23, no. 5, pp. 941–955, 2002. View at Publisher · View at Google Scholar · View at Scopus
  53. N. Klepac, S. HajnÅek, and V. Trkulja, “Cognitive performance in nondemented nonpsychotic parkinson disease patients with or without a history of depression prior to the onset of motor symptoms,” Journal of Geriatric Psychiatry and Neurology, vol. 23, no. 1, pp. 15–26, 2010. View at Publisher · View at Google Scholar · View at Scopus
  54. K. Hullmann, G. Sammer, and I. Reuter, “Training of executive functions in Parkinson's disease,” in Medimont International Proceedings, pp. 143–148, 2004.
  55. A. P. París, H. G. Saleta, M. de la Cruz Crespo Maraver et al., “Blind randomized controlled study of the efficacy of cognitive training in Parkinson's disease,” Movement Disorders, vol. 26, no. 7, pp. 1251–1258, 2011. View at Publisher · View at Google Scholar · View at Scopus
  56. E. Sinforiani, L. Banchieri, C. Zucchella, C. Pacchetti, and G. Sandrini, “Cognitive rehabilitation in Parkinson's disease.,” Archives of Gerontology and Geriatrics, supplement 9, pp. 387–391, 2004. View at Google Scholar · View at Scopus
  57. J. M. Hausdorff, G. Yogev, S. Springer, E. S. Simon, and N. Giladi, “Walking is more like catching than tapping: gait in the elderly as a complex cognitive task,” Experimental Brain Research, vol. 164, no. 4, pp. 541–548, 2005. View at Publisher · View at Google Scholar · View at Scopus
  58. G. Yogev, N. Giladi, C. Peretz, S. Springer, E. S. Simon, and J. M. Hausdorff, “Dual tasking, gait rhythmicity, and Parkinson's disease: which aspects of gait are attention demanding?” European Journal of Neuroscience, vol. 22, no. 5, pp. 1248–1256, 2005. View at Publisher · View at Google Scholar · View at Scopus