Research Article

Extension of Chronological Lifespan by Hexokinase Mutation in Kluyveromyces lactis Involves Increased Level of the Mitochondrial Chaperonin Hsp60

Figure 1

Chronological lifespan of yeast K. lactis. (a) Comparison of chronological survival of wild type JA6 grown in either glucose 2% and glycerol 2%. (b) Comparison of chronological survival in YPD medium of wild type strain and several mutants in glucose repression pathway. For each analysis (a, b) aliquots of cultures were counting over time and serial dilutions were plated on solid medium. Colony forming units were counted after 3 days. Data are representative of at least three independent experiments, mean ± s.d.
946586.fig.001a
(a)
946586.fig.001b
(b)