Effect of Dementia on the Use of Drugs for Secondary Prevention of Ischemic Heart Disease
Table 1
Characteristics of study participants in 1992 and 1998, stratified by dementia status*.
Characteristic
1992 (study year 5)† Number (%)
1998 (study year 11)‡ Number (%)
Without dementia (n = 1,005)
With dementia ()
value
Without dementia ()
With dementia ()
value
Age, years
<0.0001
<0.0001
≤75
562 (55.9)
25 (31.0)
76 (11.3)
7 (3.7)
76–85
408 (40.6)
44 (54.3)
447 (66.6)
89 (47.0)
86–95
26 (2.6)
12 (14.8)
92 (13.7)
59 (31.1)
≥96
9 (1.0)
0 (0)
56 (8.4)
35 (18.4)
Sex
0.10
0.46
Male
517 (51.4)
50 (61.0)
337 (50.1)
101 (53.2)
Female
488 (48.6)
32 (39.0)
335 (49.9)
89 (46.8)
Race
<0.0001
0.0002
White
873 (87.9)
55 (67.1)
582 (86.6)
143 (75.3)
Nonwhite
132 (13.1)
27 (32.9)
90 (13.4)
47 (24.7)
Education level
0.006
0.004
≤High school
559 (55.7)
58 (71.6)
358 (53.4)
124 (65.3)
>High school
444 (44.3)
23 (28.4)
313 (46.7)
66 (34.7)
Annual income
0.49
0.02
≤$34,999
724 (72.0)
62 (75.6)
473 (70.4)
150 (79.0)
>$35,000
281 (28.0)
20 (24.4)
199 (29.6)
40 (21.0)
ADL score, mean (SD)
0.17 (0.6)
0.54 (1.1)
<0.0001
0.41 (0.9)
1.63 (2.0)
<0.0001
COPD
167 (16.8)
10 (12.5)
0.31
150 (22.3)
35 (18.4)
0.28
270 (27.3)
40 (50.6)
<0.0001
166 (29.4)
52 (51.5)
<0.0001
Diabetes
167 (16.6)
15 (18.3)
0.70
161 (24.0)
44 (23.3)
0.83
Hyperlipidemia
592 (59.2)
54 (67.5)
0.15
408 (61)
124 (66.3)
0.18
Hypertension
470 (47.5)
41 (51.2)
0.51
336 (60.0)
72 (62.1)
0.68
Kidney disease
183 (18.2)
26 (31.7)
0.003
90 (13.4)
43 (22.6)
0.002
Stroke
79 (7.8)
24 (29.3)
<0.0001
138 (21.3)
60 (33.9)
<0.001
Comorbidity
0.002
0.02
<3 comorbid conditions
968 (96.3)
73 (89)
598 (89.0)
157 (82.6)
≥3 comorbid conditions
37 (3.68)
9 (11)
74 (11.0)
33 (17.4)
Died
0 (0)
1 (1.2)
0.08
28 (4.2)
29 (59.3)
<0.0001
Follow-up, years, mean (SD)
5.20 (1.81)
0.59 (0.06)
<0.0001
6.27 (0.63)
3.14 (1.34)
<0.0001
ADL: activities of daily living; CES-D: Center for Epidemiological Studies Depression Scale; COPD: chronic obstructive pulmonary disease; SD: standard deviation.
*Because of rounding, percentages may not total 100. †Study year 5 for initial sample and baseline year for supplemented minority cohort. ‡Final study year for full sample. Depression indicated with a score of >7 on the CES-D.
