Matrix Metalloproteinase-1 Gene Polymorphism Associated with Ultrasound-Assessed Carotid Thickness among Older Adults

Table 1

Anthropometric, clinical, metabolic, and inflammatory variables of the sample according to the genotypic group.

Variables	rs495366 genotypes
	GG ()	A_ ()
Age (years)	79.5 ± 9.3	79.2 ± 8.3	0.745
Male (%)	32.2	28.1	0.398
BMI (kg·m^−2)	26.9 ± 4.9	26.9 ± 5.1	0.841
WC (cm)	96.3 ± 12.4	94.7 ± 11.4	0.169
SBP (mm Hg)	138.8 ± 20.4	142.0 ± 21.2	0.150
DBP (mm Hg)	78.1 ± 11.0	77.2 ± 11.5	0.268
SAH (%)	76.4	76.0	0.929
Glucose level (mg·dl^−1)	101.8 ± 22.6	105.4 ± 43.0	0.659
HbA1c (%)	6.0 ± 0.9	6.1 ± 1.3	0.365
DM2 (%)	25.3	21.4	0.374
Total cholesterol (mg·dl^−1)	194.4 ± 40.0	203.2 ± 84.2	0.297
Triglycerides (mg·dl^−1)	131.5 ± 58.8	135.3 ± 62.6	0.498
HDL-c (mg·dl^−1)	51.7 ± 12.9	51.5 ± 13.2	0.988
LDL-c (mg·dl^−1)	113.2 ± 34.1	115.9 ± 36.2	0.407
VLDL-c (mg·dl^−1)	29.3 ± 13.4	30.0 ± 13.9	0.482
Creatinine clearance (ml·min^−1)	60.3 ± 26.4	55.6 ± 24.1	0.120
CRP (mg·dl^−1)	1.61 [2.25]	1.70 [3.10]	0.636
TSH (mIU·l^−1)	2.16 [2.05]	2.15 [2.53]	0.976
TNF	0.00 [0.60]	0.00 [0.34]	0.684
IL12	0.00 [8.92]	0.00 [8.93]	0.551
IL10	0.84 [2.84]	1.24 [2.94]	0.599
Sedentary (%)	59.2	63.0	0.453
Smoker (%)	19.5	17.2	0.561
Right cIMT (mm)	1.28 ± 0.60	1.40 ± 0.66	0.087
Left cIMT (mm)	1.27 ± 0.60	1.44 ± 0.64	0.041

Data are expressed as average ± standard deviation for normally distributed continuous parameters, relative frequencies within genotype for categorical features, and median with the interquartile range in brackets for nonnormally distributed continuous variables. BMI = body mass index; WC = waist circumference; HbA1c = glycated hemoglobin A1c; DM2 = type 2 diabetes mellitus; VLDL-c = very low-density lipoprotein cholesterol; LDL-c = low-density lipoprotein cholesterol; HDL-c = high-density lipoprotein cholesterol; SBP = systolic blood pressure; DBP = diastolic blood pressure; SAH = systemic arterial hypertension; CRP = C-reactive protein; TSH = thyroid-stimulating hormone; cIMT = carotid intima-media thickness.