Research Article

Tomato Powder Modulates NF-κB, mTOR, and Nrf2 Pathways during Aging in Healthy Rats

Table 2

Effects of TP supplementation on serum and liver MDA levels and liver antioxidant enzymes in healthy rats.

MarkersGroups (age at examination)
10 weeks old77 weeks old
ControlTPControlTP

Serum MDA (nmol/mL)1.31 ± 0.06c0.97 ± 0.08d2.76 ± 0.09a1.83 ± 0.06b0.003
Liver MDA (nmol/mg protein)4.60 ± 0.15c3.16 ± 0.21d7.72 ± 0.56a5.50 ± 0.22b0.001
Liver SOD (U/mg protein)184.07 ± 5.50b234.48 ± 6.99a123.21 ± 8.35d157.52 ± 8.29c0.001
Liver CAT (U/mg protein)265.88 ± 11.30b289.51 ± 9.16a204.38 ± 7.63d226.43 ± 9.19c0.008
Liver GPx (U/mg protein)33.26 ± 1.10b46.20 ± 1.33a15.55 ± 1.81d24.38 ± 0.93c0.01

MDA: malondialdehyde; SOD: superoxide dismutase; CAT: catalase; GPx: glutathione peroxidase. Data are the standard error of the mean (SEM). Mean values within a row with different superscript letters were significantly different at .