Tomato Powder Modulates NF-κB, mTOR, and Nrf2 Pathways during Aging in Healthy Rats
Table 2
Effects of TP supplementation on serum and liver MDA levels and liver antioxidant enzymes in healthy rats.
Markers
Groups (age at examination)
10 weeks old
77 weeks old
Control
TP
Control
TP
Serum MDA (nmol/mL)
1.31 ± 0.06c
0.97 ± 0.08d
2.76 ± 0.09a
1.83 ± 0.06b
0.003
Liver MDA (nmol/mg protein)
4.60 ± 0.15c
3.16 ± 0.21d
7.72 ± 0.56a
5.50 ± 0.22b
0.001
Liver SOD (U/mg protein)
184.07 ± 5.50b
234.48 ± 6.99a
123.21 ± 8.35d
157.52 ± 8.29c
0.001
Liver CAT (U/mg protein)
265.88 ± 11.30b
289.51 ± 9.16a
204.38 ± 7.63d
226.43 ± 9.19c
0.008
Liver GPx (U/mg protein)
33.26 ± 1.10b
46.20 ± 1.33a
15.55 ± 1.81d
24.38 ± 0.93c
0.01
MDA: malondialdehyde; SOD: superoxide dismutase; CAT: catalase; GPx: glutathione peroxidase. Data are the standard error of the mean (SEM). Mean values within a row with different superscript letters were significantly different at .