Research Article

Consumption of Nuts at Midlife and Healthy Aging in Women

Table 2

Odds of healthy aging, according to frequency of total consumption of nuts at midlife in the Nurses’ Health Study.

Servings (28 grams for nuts and 15 grams for peanut butter)
<1/month1–<4/month1–<2/week2–<3/week≥3/week trend

Total nuts
 Healthy agers (n = 5,538), %6.621.621.614.835.3
 Age-adjusted OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.02 (0.90, 1.17)1.02 (0.89, 1.16)1.05 (0.91, 1.21)1.18 (1.04, 1.34)<0.0001
 Multivariable-adjusteda OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.07 (0.93, 1.24)1.04 (0.90, 1.20)1.08 (0.93, 1.25)1.14 (1.00, 1.31)0.031
 Multivariable-adjustedb OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.06 (0.92, 1.22)1.02 (0.88, 1.17)1.05 (0.90, 1.22)1.10 (0.96, 1.26)0.160

Total nuts excluding peanut butter
 Healthy agers (n = 5,538), %20.835.220.28.215.6
 Age-adjusted OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.12 (1.03, 1.22)1.17 (1.07, 1.29)1.32 (1.17, 1.49)1.46 (1.32, 1.62)<0.0001
 Multivariable-adjusteda OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.10 (1.01, 1.20)1.08 (0.97, 1.19)1.14 (1.00, 1.31)1.21 (1.09, 1.35)0.001
 Multivariable-adjustedb OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.08 (0.99, 1.18)1.04 (0.94, 1.15)1.09 (0.95, 1.25)1.14 (1.02, 1.28)0.046

aLogistic regression model adjusted for age (years), education in 1992 (registered nurse, bachelor’s degree, and master or doctorate), marital status in 1996 (widowed, married, and single/separated/divorced), census tract median income (quintiles), BMI (kg/m2; <22, 22–24.9, 25–29.9, and ≥30), energy intake (quintiles of kcal/day), multivitamin use (yes/no), aspirin use (<1, 1‐2, or >2 tablets/week), pack-years of smoking (quintiles), physical activity (quintiles of METs-h/week), and physical function impairment in 2000 (yes/no). All covariates were collected in 1998 unless stated otherwise. bLogistic regression model further adjusted for Alternative Healthy Eating Index-2010 score (quintiles), excluding nuts as a component.