Journal of Aging Research

New Strategies to Fight against Sarcopenia at Old Age

Publishing date
01 Feb 2012
Submission deadline
01 Aug 2011

1Human Nutrition Unit, Research Center of Human Nutrition (CRNH Auvergne), INRA, UMR 1019, 63000 Clermont-Ferrand, France

2University of Nice Sophia Antipolis, Pole of Gerontology, UMR 6267, INSERM U998, Nice, France

3University of Nice Sophia Antipolis, Nutritional Support Unit, INSERM U907, Nice, France

4Institute for Biomedicine of Ageing, Universität Erlangen-Nürnberg, 90419 Nürnberg, Germany

New Strategies to Fight against Sarcopenia at Old Age


Aging is associated with a progressive loss of muscle mass and strength, a process called sarcopenia. The most evident metabolic explanation for muscle decline in elderly people is an imbalance between protein synthesis and breakdown rates, but other causes like neurodegenerative processes, reduction in anabolic hormone productions or sensitivity such insulin, growth, and sex hormones, dysregulation of cytokine secretions, modifications in the response to inflammatory events, inadequate nutritional intakes, and sedentary lifestyle are involved. The sequela of sarcopenia often contributes to frailty, decreased independence, and subsequently increased health care costs.

We invite investigators to contribute original research and review articles that will help to understand the biochemical, molecular, and physiological mechanisms behind aging, as well as new strategies to delay or even fight against sarcopenia. Potential topics include, but are not limited to:

  • New strategies and/or therapeutics in sarcopenia
  • Biomarkers in sarcopenia
  • Knowledge of molecular and cellular mechanisms controlling protein wasting
  • Muscle performance and sarcopenia/physical activity and sarcopenia
  • Specific amino acids supplementation and aging/frailty/sarcopenia
  • Protein intakes and quality of dietary proteins: qualitative and quantitative aspects, daily protein feeling pattern, and aging/frailty/sarcopenia
  • Role of neuropeptides in control of appetite with aging, in relation to sarcopenia
  • Autophagy/Macroautophagy and aging: apoptosis and aging, in relation to sarcopenia
  • Antioxidants and aging/sarcopenia
  • Hormone replacement and sarcopenia
  • Development of sarcopenic obesity and insulin resistance in the elderly/Prevention of obesity/muscle impairment (modulation by calorie restriction by example)
  • Pharmaconutrients and sarcopenia
  • Cytokine inhibitors and sarcopenia
  • Cognitive function and sarcopenia
  • Potential roles of gender and ethnic differences in the consequences of sarcopenia
  • Psychological and social dimensions of sarcopenia
  • Role of central/peripheral nervous system in sarcopenia

Articles published in this special issue will not be subject to the journal's Article Processing Charges.

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:


  • Special Issue
  • - Volume 2012
  • - Article ID 676042
  • - Editorial

New Strategies to Fight against Sarcopenia at Old Age

Dominique Meynial-Denis | Olivier Guérin | ... | Cornel Christian Sieber
  • Special Issue
  • - Volume 2012
  • - Article ID 754739
  • - Review Article

Sarcopenia: A Major Challenge in Elderly Patients with End-Stage Renal Disease

Maciej Domański | Kazimierz Ciechanowski
  • Special Issue
  • - Volume 2012
  • - Article ID 510801
  • - Review Article

Nutrition and Sarcopenia: A Review of the Evidence and Implications for Preventive Strategies

Siân Robinson | Cyrus Cooper | Avan Aihie Sayer
  • Special Issue
  • - Volume 2012
  • - Article ID 426278
  • - Clinical Study

Effects of High-Speed Power Training on Muscle Performance and Braking Speed in Older Adults

Stephen P. Sayers | Kyle Gibson
  • Special Issue
  • - Volume 2012
  • - Article ID 109013
  • - Review Article

Alternative Exercise Technologies to Fight against Sarcopenia at Old Age: A Series of Studies and Review

Wolfgang Kemmler | Simon von Stengel
  • Special Issue
  • - Volume 2012
  • - Article ID 251217
  • - Review Article

Novel Intriguing Strategies Attenuating to Sarcopenia

Kunihiro Sakuma | Akihiko Yamaguchi
  • Special Issue
  • - Volume 2012
  • - Article ID 629637
  • - Clinical Study

Intramuscular Adipose Tissue, Sarcopenia, and Mobility Function in Older Individuals

Robin L. Marcus | Odessa Addison | ... | Paul LaStayo
  • Special Issue
  • - Volume 2012
  • - Article ID 316943
  • - Review Article

Rationale for Antioxidant Supplementation in Sarcopenia

Francesco Cerullo | Giovanni Gambassi | Matteo Cesari
Journal of Aging Research
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