Journal of Aging Research

White Matter Changes: New Perspectives on Imaging, Clinical Aspects, and Intervention


Publishing date
15 Sep 2011
Status
Published
Submission deadline
15 Mar 2011

Lead Editor

1Department of Neurosciences and Mental Health, Hospital de Santa Maria, University of Lisbon, 1649-004 Lisbon, Portugal

2Department of Neurological and Psychiatric Sciences, University of Florence, 50121 Florence, Italy

3Department of Neurology and Alzheimer Center, VU University Medical Center, 1007 MB Amsterdam, The Netherlands


White Matter Changes: New Perspectives on Imaging, Clinical Aspects, and Intervention

Description

White matter changes (WMCs) are frequent in the elderly population and are associated with the transition from a healthy and independent status to disability and dependency. Factors such as decreased mobility, mood changes, presence of vascular risk factors, and impairment in cognition are responsible for this transition. The last decade has brought a high number of studies that tried to identify the mechanisms that underline the relation between WMC and functional impairment. This increased interest on WMC led us to new perspectives on early diagnosis, evaluation (clinical, imaging, and neuropsychological), and intervention.

We would like to invite authors to submit original studies and research articles, as well as review articles, that will contribute to the understanding of the relation between WMC and dependency among the elderly. We are particularly interested in new approaches on early diagnosis and evaluation of progression and, specially, on pharmacological and nonpharmacological interventions including therapies directed to family members or caregivers. Potential topics include, but are not limited to:

  • Epidemiology: prevalence and risk factors
  • Diagnosis: clinical features (motor, mood, urinary and cognitive characteristics, and disability), neuropsychological evaluation (instruments and interpretation of the results), and radiological aspects (instruments and rating methods)
  • Intervention: prevention and control of risk factors (evidence based) and nonpharmacological therapies directed to the patient and the family
  • Future perspectives: special attention will be given to future directions on intervention (data from existing publications including basic science approaches) and use of new imaging techniques

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jar/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 841913
  • - Editorial

White Matter Changes: New Perspectives on Imaging, Clinical Aspects, and Intervention

Sofia Madureira | Ana Verdelho | ... | Philip Scheltens
  • Special Issue
  • - Volume 2011
  • - Article ID 286564
  • - Review Article

White Matter Changes in Bipolar Disorder, Alzheimer Disease, and Mild Cognitive Impairment: New Insights from DTI

Aikaterini Xekardaki | Panteleimon Giannakopoulos | Sven Haller
  • Special Issue
  • - Volume 2011
  • - Article ID 606871
  • - Research Article

Anatomical Correlates of Age-Related Working Memory Declines

Evan T. Schulze | Elizabeth K. Geary | ... | Deborah M. Little
  • Special Issue
  • - Volume 2011
  • - Article ID 978761
  • - Review Article

Lessons from a Mouse Model Characterizing Features of Vascular Cognitive Impairment with White Matter Changes

Masafumi Ihara | Hidekazu Tomimoto
  • Special Issue
  • - Volume 2011
  • - Article ID 407074
  • - Review Article

Practice-Oriented Retest Learning as the Basic Form of Cognitive Plasticity of the Aging Brain

Lixia Yang
  • Special Issue
  • - Volume 2011
  • - Article ID 481745
  • - Research Article

Diffusion Tensor Imaging Evaluation of Corticospinal Tract Hyperintensity in Upper Motor Neuron-Predominant ALS Patients

Venkateswaran Rajagopalan | Didier Allexandre | ... | Erik P. Pioro
  • Special Issue
  • - Volume 2011
  • - Article ID 362189
  • - Research Article

Genetic Risk Factors for Longitudinal Changes in Structural MRI in Former Organolead Workers

Bryan D. James | Brian Caffo | ... | Brian S. Schwartz
  • Special Issue
  • - Volume 2011
  • - Article ID 280630
  • - Research Article

Progression of White Matter Lesion Volume and Health-Related Quality of Life in Patients with Symptomatic Atherosclerotic Disease: The SMART-MR Study

Anne M. Grool | Yolanda van der Graaf | ... | Mirjam I. Geerlings
  • Special Issue
  • - Volume 2011
  • - Article ID 187219
  • - Research Article

Striatal Hypodensities, Not White Matter Hypodensities on CT, Are Associated with Late-Onset Depression in Alzheimer's Disease

Jessica A. Brommelhoff | Bryan M. Spann | ... | Margaret Gatz
  • Special Issue
  • - Volume 2011
  • - Article ID 281274
  • - Research Article

Fiber Tracts Anomalies in APPxPS1 Transgenic Mice Modeling Alzheimer's Disease

H. Chen | S. Epelbaum | B. Delatour
Journal of Aging Research
 Journal metrics
Acceptance rate19%
Submission to final decision119 days
Acceptance to publication35 days
CiteScore3.200
Impact Factor-
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