Journal of Biomarkers / 2013 / Article / Fig 1

Research Article

Association between a Tetranucleotide Repeat Polymorphism of SPAG16 Gene and Cataract in Male Children

Figure 1

Cytogenetic localization at 2q34 of markers associated with cataract and location of D2S2944 marker in SPAG16 gene. (a) known markers in the region flanked by D2S1384 and D2S2361 are shown. The ruler in the partial map of chromosome 2 shows the relative nucleotide position expressed in mega bases (205Mb–215 Mb) and all the markers distances are according to NCBI: Mapviewer. Marshfield shows markers D2S2944, D2S2361, D2S128 at genetic map position 210.43cM. Alleles of the microsatellite marked in figure are reported to form the disease haplotype linked to congenital/pediatric cataract. (b) From the NCBI Reference Sequence: NW_001838863.1 showing 420.70kb region from base 39766685 to 40187388. Superscripts correspond to references: Nandrot et al., (2003) [5], Iyengar et al., (2004) [6], Mackay et al., (2004) [7], Rogaev et al., (1996) [8], Stephan et al. (1999) [9], Shentu et al., (2004) [10], Li et al., (2008) [11], and Zhang et al., (2009) [12].
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