Journal of Biomarkers / 2013 / Article / Fig 3

Research Article

Association between a Tetranucleotide Repeat Polymorphism of SPAG16 Gene and Cataract in Male Children

Figure 3

Structure analysis of transcripts containing different number of tetra repeats of D2S2944 marker. MFOLD predicted stem-loop structure depending on the number of repeats in the microsatellite sequence of D2S2944 (GenBank: G08147.1) present in the intron 10 of SPAG16 gene. Energetically more favorable stem-loop structure are formed in presence of >(GATA)13 repeats.
(a)  (GATA)09 repeat containing motif: 25th 61st nucleotide
(b) (GATA)12 repeat containing motif: 25th 73rd nucleotide
(c) (GATA)15 repeat containing motif: 25th 85th nucleotide of the PCR product sequence as in GenBank: G08147.1

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