Research Article

Functional Epigenetic Analysis of Prostate Carcinoma: A Role for Seryl-tRNA Synthetase?

Table 3

mRNA expression changes of candidate genes represented by statistical analysis*.

Genes valueDownregulation prevalence
(normal versus tumor)
Fold changes
(normal versus tumor)
≥−1.5-fold changes prevalence
(normal versus tumor)

SPRY40.000774% (37/50)−1.6484% (31/37)
SARS 0.000184% (42/50)−1.4455% (23/42)
GADD45A 0.000188% (44/50)−2.3284% (37/44)
GSTP1 0.000190% (45/50)−2.5484% (42/45)

Considered significances ( ) calculated with Wilcoxon signed rank test for all genes. Normal versus tumor common downregulation and ≥−1.5-fold changes prevalence among downregulated samples.