Research Article

Biomarkers Predict Relapse in Granulomatosis with Polyangiitis

Table 2

Clinical yield of a series of relapse biomarkers in 30 patients with GPA.

BiomarkerClinical yield if <baselineClinical yield if >baseline value

White cell count11.22%30.21%0.01
Neutrophil count11.98%31.43%0.01
Lymphocyte count18.13%23.53%0.92
Monocyte count20.23%21.40%0.63
ANCA titre18.24%22.79%0.7
Anti-PR3 antibodies7.86%24.81%0.0003
CRP15.67%32.31%0.002
Creatinine17.33%23.40%0.74
Neutrophil count, CRP, and anti-PR314.81%58.89%0.02