Research Article
Biomarkers Predict Relapse in Granulomatosis with Polyangiitis
Table 2
Clinical yield of a series of relapse biomarkers in 30 patients with GPA.
| Biomarker | Clinical yield if <baseline | Clinical yield if >baseline | value |
| White cell count | 11.22% | 30.21% | 0.01 | Neutrophil count | 11.98% | 31.43% | 0.01 | Lymphocyte count | 18.13% | 23.53% | 0.92 | Monocyte count | 20.23% | 21.40% | 0.63 | ANCA titre | 18.24% | 22.79% | 0.7 | Anti-PR3 antibodies | 7.86% | 24.81% | 0.0003 | CRP | 15.67% | 32.31% | 0.002 | Creatinine | 17.33% | 23.40% | 0.74 | Neutrophil count, CRP, and anti-PR3 | 14.81% | 58.89% | 0.02 |
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