Journal of Biomarkers / 2014 / Article / Tab 3 / Research Article
Diagnosis of Non-ST-Elevation Acute Coronary Syndrome by the Measurement of Heart-Type Fatty Acid Binding Protein in Serum: A Prospective Case Control Study Table 3 Receiver operating characteristics curve analysis.
Test characteristic CTnI cTnT H-FABP Criterion >0.009
g/L >9
g/L >6.5 ng/mL Area under the ROC curve (AUC) 0.73 0.71 0.79 95% Confidence interval 0.59 to 0.84 0.57 to 0.83 0.66 to 0.89 Significance level P (Area = 0.5) 0.0003 0.002 <0.0001 Sensitivity 40 46.7 56.7 95% CI 22.7–59.4 28.3–65.7 37.4–74.5 Specificity 100 100 100 95% CI 84.6–100.0 84.6–100.0 84.6–100.0 +LR 1.2 1.7 12.47 95% CI 0.8–1.9 1.0–3.0 1.8–86.8 −LR 0.6 0.53 0.43 95% CI 0.4–0.8 0.4–0.7 0.3–0.7 +PV 100 100 100 95% CI 73.5–100.0 76.8–100.0 79.4–100.0 −PV 55 57.9 62.9 95% CI 38.5–70.7 40.8–73.7 44.9–78.5
+PV: positive predictive value, −PV: negative predictive value, +LR: positive likelihood ratio, and −LR: negative likelihood ratio.