Biomarkers for Detection and Monitoring of B16 Melanoma in Mouse Urine and Feces
Table 6
VOCs with higher or lower concentrations in the feces of tumor-bearing mice than of healthy mice.
Number
RT (min)
Fold (%)
value1
H-C
H-E
H-L
E-L
1
6.71
223
<0.01
0.27
<0.01
<0.01
2
6.87
186
<0.01
0.83
<0.01
<0.01
3
6.94
132
<0.01
0.84
<0.01
<0.01
4
8.24
163
<0.01
0.10
<0.01
0.02
5
8.40
186
0.01
0.07
0.01
0.05
6
8.58
199
<0.01
0.03
0.02
0.03
7
8.67
116
0.84
0.20
0.43
0.03
8
10.21
204
<0.01
0.02
<0.01
0.21
9
10.79
135
0.03
0.51
0.01
0.02
10
13.39
120
0.18
<0.01
0.55
<0.01
11
14.95
122
0.52
<0.01
0.13
<0.01
12
16.29
86
0.90
0.37
0.59
0.05
13
16.76
149
0.28
0.08
0.70
0.09
Calculated by using a two-tailed paired -test. values smaller than 0.05 are marked in bold. H: healthy; E: early melanoma; L: late melanoma; C: cancer; both E and L.
