Figure 1: Flow chart of patient selection.Patients with positive tuberculin skin test or positive interferon-gamma release assay and clinical, radiological, or culture evidence of tuberculosis.Positive tuberculin skin test and positive interferon-gamma release assay or only a positive interferon-gamma release assay with no clinical, radiological, or culture evidence of tuberculosis.Healthy relatives testing negative by interferon-gamma release assay and/or tuberculin skin test during contact screening.