Research Article
Determination of Urinary Neopterin/Creatinine Ratio to Distinguish Active Tuberculosis from Latent Mycobacterium tuberculosis Infection
| ā | Patients with tuberculosis () | Patients with latent Mycobacterium tuberculosis infection () | Healthy controls () |
| Age in years (median (range)) | 14.7 (5.8 to 37) | 14.7 (4.5 to 49) | 24 (9 to 40) |
| Gender (female) | 7 | 19 | 6 |
| Manifestations of disease | 9 pulmonary tuberculosis, 3 extrapulmonary tuberculosis (1 each lymphadenitis, mandibular, and peritoneal) | No disease manifestations | No disease manifestations |
| Isolation of Mycobacterium tuberculosis | 6/9 patients with pulmonary tuberculosis, and one each with tuberculous lymphadenitis, and mandibular tuberculosis | N/A | N/A |
| Urinary neopterin/creatinine ratio (micromole/mol, median (range)) | 374.1 (129.0 to 1072.3) | 142.1 (28.0 to 384.1) | 146.0 (40.3 to 200.0) |
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