Journal of Biophysics / 2009 / Article / Tab 3

Research Article

Tropomyosin Period 3 Is Essential for Enhancement of Isometric Tension in Thin Filament-Reconstituted Bovine Myocardium

Table 3

MgATP2- sensitivity and cooperativity of relaxation. *P value ≤ .05 compared to nfTm; **P value ≤ .01 compare to nfTm; else, P value > 0.05. The Hill factor (g) and pS50 (MgATP2- sensitivity) were deduced by fitting the pS-tension (or stiffness) data to (2), where pS = –log10(S) and S = [MgATP]. In all experiments, temperature was 25°C, ionic strength was 200 mM, and pH was adjusted to 7.00. The data were individually fitted to (2), averaged, and tabulated with SEM.

nf Units

Number of expts.554
Based on tension
g7.8 ± 3.15.9 ± 4.07.1 ± 3.6
pS505.12 ± 0.055.00 ± 0.084.95 ± 0.0
Based on stiffness
g2.1 ± 0.52.0 ± 0.53.0 ± 0.9
pS505.28 ± 0.055.22 ± 0.094.99 ± 0.0

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