Review Article
CRASH-2 Study of Tranexamic Acid to Treat Bleeding in Trauma Patients: A Controversy Fueled by Science and Social Media
Table 4
Editorials on TXA use.
| | Title | Author | Description | Year | Outcomes | Recommendations |
| | CRASH-2 Goes Viral [21] | The Lancet | Editorial (Internet) | 2011 | Reviews CRASH-2 media coverage | Recommends TXA in trauma |
| | Antifibrinolytics in trauma patients [24] | Kenji Inaba | Editorial (Internet/print) | 2012 | Reviews
CRASH-2 MATTERs | Cites CRASH-2 “challenges” and notes MATTERs clarity |
| | Trauma and Tranexamic Acid [22] | Gruen et al. | Editorial (Print) | 2013 | Reviews knowledge gaps noted by
Napolitano et al. and Pusateri et al. | Recommends that TXA be confirmed in future RCTs |
| | CRASH2, MATTERS…TXA in Trauma [23] | Mark Putland | Editorial (Internet/ blog) | 2013 | Reviews CRASH-2 MATTERs, MATTERs II | Data for seizures and thromboembolic complications remain incomplete. Needs more study. |
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