Journal of Blood Transfusion

Quality and Safety of Blood Products


Publishing date
23 Dec 2016
Status
Published
Submission deadline
05 Aug 2016

1Canadian Blood Services, Ottawa, Canada

2Australian Red Cross Blood Service, Sydney, Australia

3University of Alberta, Edmonton, Canada

4Canadian Blood Services, Hamilton, Canada


Quality and Safety of Blood Products

Description

Blood products, including platelet concentrates, red blood cell concentrates, and plasma, are biological pharmaceuticals which should meet the highest quality and safety standards. Good Manufacturing Practices (GMP) have been broadly adopted as the main tool for quality assurance of blood products. Similarly, several strategies including donor screening, skin disinfection methods, first aliquot diversion, and bacterial detection methods have been implemented to decrease the incidence of transfusion-associated septic events. Although there is a consensus that some or all of these measures are in operation worldwide, uncertainty still exists about variation of practice in different blood suppliers. Major considerations that challenge the consistency in quality and safety of blood products are the biological nature of raw material, differences in manufacturing processes, and variation in testing methods.

We invite original and review manuscripts describing current and under-development practices related to improving the quality and safety of blood products.

Potential topics include, but are not limited to:

  • Quality assurance practices for platelet concentrates, red blood cell concentrates, and plasma
  • New approaches and technologies to improve the quality of blood products
  • Understanding the biological characteristics of each of the blood products (“what is in the bag”)
  • Blood product quality markers associated with international standards
  • Blood product quality markers associated with quality monitoring programs
  • Safety practices for platelet concentrates, red blood cell concentrates, and plasma:
    • Donor screening and deferrals
    • Skin disinfection
    • First aliquot diversion
    • Testing for viral, bacterial, and parasitic infections: current and under-development methods
    • Pathogen reduction technologies
  • Practices to manage blood product safety including approaches when screening assays are not available or have not been implemented
  • Emerging pathogens

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 2482157
  • - Editorial

Quality and Safety of Blood Products

Sandra Ramirez-Arcos | Denese C. Marks | ... | William P. Sheffield
  • Special Issue
  • - Volume 2016
  • - Article ID 4860284
  • - Review Article

Quality Assessment of Established and Emerging Blood Components for Transfusion

Jason P. Acker | Denese C. Marks | William P. Sheffield
  • Special Issue
  • - Volume 2016
  • - Article ID 6140239
  • - Review Article

Could Microparticles Be the Universal Quality Indicator for Platelet Viability and Function?

Elisabeth Maurer-Spurej | Kate Chipperfield
  • Special Issue
  • - Volume 2016
  • - Article ID 6260792
  • - Research Article

Stability of Thawed Apheresis Fresh-Frozen Plasma Stored for up to 120 Hours at 1°C to 6°C

William P. Sheffield | Varsha Bhakta | ... | Craig Jenkins
  • Special Issue
  • - Volume 2016
  • - Article ID 3059848
  • - Research Article

Mitigating the Risk of Transfusion-Transmitted Dengue in Australia

Kelly Rooks | Clive R. Seed | ... | Helen M. Faddy
  • Special Issue
  • - Volume 2016
  • - Article ID 9647675
  • - Research Article

A Comparative Study of Assay Performance of Commercial Hepatitis E Virus Enzyme-Linked Immunosorbent Assay Kits in Australian Blood Donor Samples

Ashish C. Shrestha | Robert L. P. Flower | ... | Helen M. Faddy
  • Special Issue
  • - Volume 2016
  • - Article ID 2920514
  • - Research Article

A New Proof of Concept in Bacterial Reduction: Antimicrobial Action of Violet-Blue Light (405 nm) in Ex Vivo Stored Plasma

Michelle Maclean | John G. Anderson | ... | Chintamani D. Atreya
  • Special Issue
  • - Volume 2016
  • - Article ID 9316385
  • - Research Article

Quantification of Cell-Free DNA in Red Blood Cell Units in Different Whole Blood Processing Methods

Andrew W. Shih | Vinai C. Bhagirath | ... | Patricia C. Liaw

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