Table of Contents
Journal of Catalysts
Volume 2013, Article ID 392162, 8 pages
Research Article

Microwave-Assisted Synthesis of Spirofused Heterocycles Using Decatungstodivanadogermanic Heteropoly Acid as a Novel and Reusable Heterogeneous Catalyst under Solvent-Free Conditions

Laboratory of Heterocycles, School of Studies in Chemistry and Biochemistry, Vikram University, Ujjain 456010, Madhya Pradesh, India

Received 8 October 2012; Accepted 7 January 2013

Academic Editor: Mohammed M. Bettahar

Copyright © 2013 Srinivasa Rao Jetti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Decatungstodivanadogermanic acid (H6GeW10V2O40·22H2O) was synthesized and used as a novel, green heterogeneous catalyst for the synthesis of spirofused heterocycles from one-pot three-component cyclocondensation reaction of a cyclic ketone, aldehyde, and urea in high yields under solvent-free condition in microwave irradiation at 80°C. This catalyst is efficient not only for cyclic ketones, but also for cyclic β-diketones, β-diester, and β-diamide derivatives such as cyclohexanone, dimedone, and Meldrum's acid, or barbituric acid derivatives.