Clinical Study

Refractory Status Epilepticus: Experience in a Neurological Intensive Care Unit

Table 5

Univariate analysis of factors associated with unfavorable short-term functional outcome.

FactorOR95% CI value

Age >60 years61.6–22.460.04
APACHE II Score ≥152.811.10–7.190.028
Etiology: stroke3.41.18–9.770.019
Etiology: CNS infection2.270.44–11.770.26
Etiology: anoxia/hypoxia1.550.28–8.560.47
Etiology: brain tumor0.370.05–2.380.27
Etiology: traumatic brain injury1.90.36–10.130.36
Systemic abnormalities1.850.18–18.640.51
Underlying epileptic disease0.130.03–0.450.001
Acute neurological lesion4.691.6–13.780.003
Coma6.92.5–19.07<0.0001
Previous treatment time >10 hours0.630.19–2.010.43
Uncontrolled RSE15.81.49–280.50.03

OR: Odds ratio; CI: confidence interval; APACHE II: The Acute Physiology and Chronic Health Evaluation Score; CNS: central nervous system; RSE: refractory status epilepticus.