Table of Contents
Journal of Critical Care Medicine
Volume 2015 (2015), Article ID 173985, 8 pages
http://dx.doi.org/10.1155/2015/173985
Research Article

Relation of Reported Sedation and Ventilator Weaning Practices to Ventilator Time in Norwegian Intensive Care Units

1Department of Anaesthesia & Intensive Care, Haukeland University Hospital, 5021 Bergen, Norway
2Norwegian Intensive Care Registry, Department of Anaesthesia & Intensive Care, Haukeland University Hospital, 5021 Bergen, Norway

Received 3 March 2015; Revised 11 May 2015; Accepted 14 May 2015

Academic Editor: Claude Guérin

Copyright © 2015 Marit Bekkevold et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. C. G. Hughes, S. McGrane, and P. P. Pandharipande, “Sedation in the intensive care setting,” Clinical Pharmacology: Advances and Applications, vol. 4, no. 1, pp. 53–63, 2012. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Barr, G. L. Fraser, K. Puntillo et al., “Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit,” Critical Care Medicine, vol. 41, no. 1, pp. 263–306, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. V. Page and E. W. Ely, Delirium in Critical Care, Cambridge University Press, Cambridge, UK, 2011.
  4. S. V. Desai, T. J. Law, and D. M. Needham, “Long-term complications of critical care,” Critical Care Medicine, vol. 39, no. 2, pp. 371–379, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. S. Ouimet, B. P. Kavanagh, S. B. Gottfried, and Y. Skrobik, “Incidence, risk factors and consequences of ICU delirium,” Intensive Care Medicine, vol. 33, no. 1, pp. 66–73, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. T. Strøm, T. Martinussen, and P. Toft, “A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial,” The Lancet, vol. 375, no. 9713, pp. 475–480, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. W. D. Schweickert, B. K. Gehlbach, A. S. Pohlman, J. B. Hall, and J. P. Kress, “Daily interruption of sedative infusions and complications of critical illness in mechanically ventilated patients,” Critical Care Medicine, vol. 32, no. 6, pp. 1272–1276, 2004. View at Publisher · View at Google Scholar · View at Scopus
  8. J. P. Kress, A. S. Pohlman, M. F. O'Connor, and J. B. Hall, “Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation,” New England Journal of Medicine, vol. 342, no. 20, pp. 1471–1477, 2000. View at Publisher · View at Google Scholar · View at Scopus
  9. T. D. Girard, J. P. Kress, B. D. Fuchs et al., “Efficacy and safety of a paired sedation and ventilator weaning guideline for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial,” The Lancet, vol. 371, no. 9607, pp. 126–134, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. C. N. Sessler and S. Pedram, “Protocolized and target-based sedation and analgesia in the ICU,” Critical Care Clinics, vol. 25, no. 3, pp. 489–513, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. Y. Skrobik, “Delirium prevention and treatment,” Critical Care Clinics, vol. 25, no. 3, pp. 585–591, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. E. W. Ely, A. Shintani, B. Truman et al., “Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit,” Journal of the American Medical Association, vol. 291, no. 14, pp. 1753–1762, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. J. W. W. Thomason, A. Shintani, J. F. Peterson, B. T. Pun, J. C. Jackson, and E. W. Ely, “Intensive care unit delirium is an independent predictor of longer hospital stay: a prospective analysis of 261 non-ventilated patients,” Critical Care, vol. 9, no. 4, pp. R375–R381, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. E. B. Milbrandt, S. Deppen, P. L. Harrison et al., “Costs associated with delirium in mechanically ventilated patients,” Critical Care Medicine, vol. 32, no. 4, pp. 955–962, 2004. View at Publisher · View at Google Scholar · View at Scopus
  15. E. E. Vasilevskis, E. W. Ely, T. Speroff, B. T. Pun, L. Boehm, and R. S. Dittus, “Reducing iatrogenic risks: ICU-acquired delirium and weakness—crossing the quality chasm,” Chest, vol. 138, no. 5, pp. 1224–1233, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. G. Brattebø, D. Hofoss, H. Flaatten, A. K. Muri, S. Gjerde, and P. E. Plsek, “Effect of a scoring system and protocol for sedation on duration of patients' need for ventilator support in a surgical intensive care unit,” British Medical Journal, vol. 324, no. 7350, pp. 1386–1389, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. P. Guldbrand, L. Berggren, G. Brattebö, J. Mälstam, E. Rönholm, and O. Winsö, “Survey of routines for sedation of patients on controlled ventilation in Nordic intensive care units,” Acta Anaesthesiologica Scandinavica, vol. 48, no. 8, pp. 944–950, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. H. Wøien, A. Stubhaug, and I. T. Bjørk, “Analgesia and sedation of mechanically ventilated patients—a national survey of clinical practice,” Acta Anaesthesiologica Scandinavica, vol. 56, no. 1, pp. 23–29, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. H. Wøien, H. Værøy, G. Aamodt, and IT. Bjørk, “Improving the systematic approach to pain and sedation management in the ICU by using assessment tools,” Journal of Clinical Nursing, vol. 23, no. 11-12, pp. 1552–1561, 2012. View at Publisher · View at Google Scholar
  20. H. Wøien, S. Balsliemke, and A. Stubhaug, “The incidence of delirium in Norwegian intensive care units; deep sedation makes assessment difficult,” Acta Anaesthesiologica Scandinavica, vol. 57, pp. 294–302, 2013. View at Google Scholar
  21. J.-R. le Gall, S. Lemeshow, and F. Saulnier, “A new simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study,” The Journal of the American Medical Association, vol. 270, no. 24, pp. 2957–2963, 1993. View at Publisher · View at Google Scholar · View at Scopus
  22. J. W. Devlin, G. Boleski, M. Mlynarek et al., “Motor Activity Assessment Scale: a valid and reliable sedation scale for use with mechanically ventilated patients in an adult surgical intensive care unit,” Critical Care Medicine, vol. 27, no. 7, pp. 1271–1275, 1999. View at Publisher · View at Google Scholar · View at Scopus
  23. C. N. Sessler, M. S. Gosnell, M. J. Grap et al., “The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients,” American Journal of Respiratory and Critical Care Medicine, vol. 166, no. 10, pp. 1338–1344, 2002. View at Publisher · View at Google Scholar · View at Scopus
  24. R. R. Riker, Y. Shehabi, P. M. Bokesch et al., “Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial,” The Journal of the American Medical Association, vol. 301, no. 5, pp. 489–499, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. J. I. Salluh, M. Soares, J. M. Teles et al., “Delirium epidemiology in critical care (DECCA): an international study,” Critical Care, vol. 14, no. 6, article R210, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. N. I. Lone and T. S. Walsh, “Prolonged mechanical ventilation in critically ill patients: epidemiology, outcomes and modelling the potential cost consequences of establishing a regional weaning unit,” Critical Care, vol. 15, article R102, 2011. View at Publisher · View at Google Scholar · View at Scopus
  27. M. H. Kollef, N. Levy, T. S. Ahrens, R. Schaiff, D. Prentice, and G. Sherman, “The use of continuous i.v. sedation is associated with prolongation of mechanical ventilation,” Chest, vol. 114, no. 4, pp. 541–548, 1998. View at Google Scholar · View at Scopus
  28. Y. Skrobik, C. Leger, M. Cossette, V. Michaud, and J. Turgeon, “Factors predisposing to coma and delirium: fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors,” Critical Care Medicine, vol. 41, no. 4, pp. 999–1008, 2013. View at Publisher · View at Google Scholar · View at Scopus
  29. G. Chanques, S. Jaber, E. Barbotte et al., “Impact of systematic evaluation of pain and agitation in an intensive care unit,” Critical Care Medicine, vol. 34, no. 6, pp. 1691–1699, 2006. View at Publisher · View at Google Scholar · View at Scopus
  30. H. Reschreiter, M. Maiden, and A. Kapila, “Sedation practice in the intensive care unit: a UK national survey,” Critical Care, vol. 12, no. 6, article R152, 2008. View at Publisher · View at Google Scholar · View at Scopus
  31. E. W. Ely, R. Margolin, J. Francis et al., “Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU),” Critical Care Medicine, vol. 29, no. 7, pp. 1370–1379, 2001. View at Publisher · View at Google Scholar · View at Scopus
  32. J.-M. Constantin, G. Chanques, B. De Jonghe et al., “Current use of sedation and analgesia: 218 resuscitations in France services practices survey,” Annales Francaises d'Anesthesie et de Reanimation, vol. 29, no. 5, pp. 339–346, 2010. View at Publisher · View at Google Scholar · View at Scopus
  33. I. Egerod, J. W. Albarran, M. Ring, and B. Blackwood, “Sedation practice in Nordic and non-Nordic ICUs: a European survey,” Nursing in Critical Care, vol. 18, no. 4, pp. 166–175, 2013. View at Publisher · View at Google Scholar · View at Scopus
  34. M. A. Tanios, M. de Wit, S. K. Epstein, and J. W. Devlin, “Perceived barriers to the use of sedation protocols and daily sedation interruption: a multidisciplinary survey,” Journal of Critical Care, vol. 24, no. 1, pp. 66–73, 2009. View at Publisher · View at Google Scholar · View at Scopus
  35. J. L. Guttormson, L. Chlan, C. Weinert, and K. Savik, “Factors influencing nurse sedation practices with mechanically ventilated patients: a U.S. national survey,” Intensive and Critical Care Nursing, vol. 26, no. 1, pp. 44–50, 2010. View at Publisher · View at Google Scholar · View at Scopus
  36. M. A. Miller, E. A. Bosk, T. J. Iwashyna, and S. L. Krein, “Implementation challenges in the intensive care unit: the why, who, and how of daily interruption of sedation,” Journal of Critical Care, vol. 27, no. 2, pp. 218.e1–218.e7, 2012. View at Publisher · View at Google Scholar · View at Scopus
  37. A. Campino, M. C. Lopez-Herrera, I. Lopez-de-Heredia, and A. Valls-I-Soler, “Medication errors in a neonatal intensive care unit. Influence of observation on the error rate,” Acta Paediatrica, vol. 97, no. 11, pp. 1591–1594, 2008. View at Publisher · View at Google Scholar · View at Scopus
  38. K. A. Fairman and F. R. Curtiss, “Still looking for health outcomes in all the wrong places? Misinterpreted observational evidence, medication adherence promotion, and value-based insurance design,” Journal of Managed Care Pharmacy, vol. 15, no. 6, pp. 501–507, 2009. View at Google Scholar · View at Scopus
  39. R. P. Patel, M. Gambrell, T. Speroff et al., “Delirium and sedation in the intensive care unit: survey of behaviors and attitudes of 1384 healthcare professionals,” Critical Care Medicine, vol. 37, no. 3, pp. 825–832, 2009. View at Publisher · View at Google Scholar · View at Scopus
  40. J. I. F. Salluh, F. Dal-Pizzol, P. V. C. Mello et al., “Delirium recognition and sedation practices in critically ill patients: a survey on the attitudes of 1015 Brazilian critical care physicians,” Journal of Critical Care, vol. 24, no. 4, pp. 556–562, 2009. View at Publisher · View at Google Scholar · View at Scopus
  41. J. W. Devlin, J. J. Fong, G. L. Fraser, and R. R. Riker, “Delirium assessment in the critically ill,” Intensive Care Medicine, vol. 33, no. 6, pp. 929–940, 2007. View at Publisher · View at Google Scholar · View at Scopus
  42. V. J. Page, S. Navarange, S. Gama, and D. F. McAuley, “Routine delirium monitoring in a UK critical care unit,” Critical Care, vol. 13, no. 1, article R16, 2009. View at Publisher · View at Google Scholar · View at Scopus
  43. J. Garnacho-Montero, R. Amaya-Villar, J. L. García-Garmendía, J. Madrazo-Osuna, and C. Ortiz-Leyba, “Effect of critical illness polyneuropathy on the withdrawal from mechanical ventilation and the length of stay in septic patients,” Critical Care Medicine, vol. 33, no. 2, pp. 349–354, 2005. View at Publisher · View at Google Scholar · View at Scopus