Journal of Cancer Epidemiology / 2009 / Article / Tab 2

Research Article

Predictors of Venous Thromboembolism in Patients with Advanced Common Solid Cancers

Table 2

Patient and cancer characteristics and rate of venous thromboembolism within 1 year after cancer diagnosis.

PredictorTotalVTE%(95% CI)P value

Male7,5792192.9(2.51–3.27)
Female6,6352704.1(3.59–4.55)<.01

Age 67–692,4271074.4(3.59–5.23)
Age 70–744,4971844.1(3.51–4.67)
Age 75–793,7911193.1(2.58–3.7)
Age 80–842,282562.5(1.82–3.08)
Age 85+1,217231.9(1.12–2.66)<.01

White12,8994393.4(3.09–3.71)
Black1,315503.8(2.77–4.83).45

Breast cancer1,789724.0(3.11–4.93)
Colon cancer1,890743.9(3.05–4.79)
Lung cancer8,1022733.4(2.98–3.76)
Prostate cancer1,596201.3(0.7–1.8)
Pancreatic cancer837506.0(4.36–7.58)<.01

Stage 36,3222213.5(3.05–3.95)
Stage 47,8922683.4(3–3.8).75

Grade 1 or 24,8671713.5(2.99–4.03)
Grade 3 or 49,3473183.4(3.03–3.77).73

Surgery5,0652044.0(3.49–4.57)<.01
Chemotherapy5,5592604.7(4.12–5.24)<.01
Radiation therapy6,0692514.1(3.64–4.64)<.01

MI384112.9(1.19–4.53).53
CHF1,059262.5(1.53–3.39).07
PVD517152.9(1.45–4.35).49
CVD687192.8(1.53–4).32
COPD2,652712.7(2.07–3.29).02
Dementia117<50.9(0–2.51).12
Diabetes1,689503.0(2.15–3.77).25
Chronic Kidney Disease160<51.9(0–3.98).28
Ulcers21362.8(0.6–5.04).62
Rheumatologic disease26493.4(1.22–5.6).98
Hip fracture395123.0(1.35–4.73).66
Atrial Fibrillation896202.2(1.26–3.2).04
Obesity10354.9(0.7–9).43

Bivariate analysis of cancer and patient characteristics on development of VTE. The following comorbid conditions were removed because of prevalences <100: paralysis, cirrhodites, AIDS, and central venous catheter. Myocardial infarction: MI; congestive heart failure: CHF; peripheral vascular disease: PVD; cerebrovascular disease: CVD; chronic obstructive pulmonary disease: COPD.

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