Chromosome 5p Region SNPs Are Associated with Risk of NSCLC among Women
Table 1
Participant characteristics.
Variable
Caucasians
African Americans
Cases
Controls
P-value
Cases
Controls
P-value
N
364
380
95
103
Age (years): Mean (sd)
61 (9)
60 (9)
.08
58 (9)
58 (9)
.83
Smoking Status: N (%)
Never
36 (10)
194 (51)
8 (8)
48 (47)
Former
132 (36)
119 (32)
24 (25)
31 (30)
Current
195 (54)
64 (17)
.0001
63 (66)
23 (23)
<.0001
Pack-years among Smokers: Mean (sd)
51 (30)
26 (23)
.0001
30 (22)
23 (23)
.07
History of COPD1: N (%)
No
242 (66)
326 (86)
72 (76)
90 (87)
Yes
122 (34)
54 (14)
.0001
23 (24)
13 (13)
.03
Family History of Lung Cancer: N (%)
No
277 (76)
334 (88)
67 (71)
92 (89)
Yes
87 (24)
46 (12)
.0001
28 (29)
11 (11)
.0009
Regular Adult Aspirin Use: N (%)
Never
272 (76)
280 (74)
77 (82)
78 (76)
Ever
86 (24)
100 (26)
.47
17 (18)
24 (24)
.35
Years of Education: Mean (sd)
13 (2)
14 (3)
.0001
12 (3)
13 (2)
.03
BMI2: Mean (sd)
26 (6)
29 (7)
.0001
27 (7)
32 (8)
<.0001
1Chronic obstructive pulmonary disease including chronic obstructive lung disease, emphysema, and chronic bronchitis. 2Body mass index = weight and height in kg/m2.
