Research Article
Weight History, Smoking, Physical Activity and Breast Cancer Risk among French-Canadian Women Non-Carriers of More Frequent BRCA1/2 Mutations
Table 1
Selected
characteristics of the study population.
| | Variables | Cases
() (%) | Controls
() (%) | |
| | Age
(years, mean ± SD) | | | .01 | | <30 | 3 | 4 | | | 31–40 | 17 | 27 | | | 41–50 | 45 | 41 | | | 51–60 | 29 | 23 | | | 61+ | 6 | 5 | | | Education
attainment (years,
mean ± SD) | | | .01 | | Marital
status | | | | | Single | 12.5 | 11.1 | | | Married/Common-law | 70.4 | 66.4 | | | Separated/divorced | 13.9 | 14.6 | | | Widowed | 3.2 | 7.9 | .15 | | Parity | | | | | Nulliparous | 27.1 | 15.4 | .01 | | ≥1 | 72.9 | 84.6 | .01 | | Menopausal
status | | | | | Yes | 203 | 145 | | | No | 77 | 135 | .01 | | Oral
contraceptive use | | | | | Ever | 87.9 | 85.0 | | | Never | 12.1 | 15.0 | .40 | | Hormone
replacement therapy | | | | | Yes | 26.8 | 33.6 | | | No | 73.2 | 66.4 | .10 | | Smoking | | | | | Ever | 63.6 | 53.6 | | | Never | 36.4 | 46.4 | .02 | | Smoking
| | | .03 | | (pack-years,
mean ± SD) | | | | | Age
at menarche(years,
mean ± SD) | | | .12 | | Age at menopause (years) | | | .20 | | Age at maximum weight(years) | | | .01 | | Current weight (lbs) | | | .10 | | Weight at the age of 20 (lbs) | | | .06 | | Weight at the age of 30 (lbs) | | | .18 | | Weight at the age of 40 (lbs) | | | .20 | | Maximum lifetime weight (lbs) | | | .04 | | Weight gain since the age of 20 (lbs) | | | .01 | | Weight gain since the age of 30 (lbs) | | | .01 | | Weight gain since the age of 40 (lbs) | | | .01 | | Physical activity (MET-hours/week) | | | | | Moderate (4) | | | .01 | | Vigorous (7) | | | .29 | | Total | | | .22 | | Total energy intake (Kcal) | | | .01 |
|
|
values are
univariate and derived by student’s t-test
for continuous variables with the χ 2 test for categorical variables.
MET: metabolic equivalent.
|
