Research Article
Weight History, Smoking, Physical Activity and Breast Cancer Risk among French-Canadian Women Non-Carriers of More Frequent BRCA1/2 Mutations
Table 2
Odd ratios and 95% confidence intervals for
breast cancer risk associated with weight history.
| | Variables | Q1 | Q2 | Q3 |
for trend |
| | Current | | | | | | Range (kg/) | ≤21.1 | >21.1 and ≤25.0 | >25.0 | | | Cases/Controls | 91/92 | 98/94 | 91/94 | | | Univariate OR (95% CI) | 1.00 | 1.34 (0.35–1.41)
| 1.76 () | .08 | | Multivariate (95% CI) | | 1.25 () | 1.55 () | .09
| | Age at maximum BMI | | | | | | Range (years) | ≤39 | >39 and ≤50 | >50 | | | Cases/Controls | 58/126 | 108/94 | 114/60 | | | Univariate OR (95%
CI) | 1.00 | 2.50 () | 2.65
() | .01 | | Multivariate (95% CI) | | 2.77 () | 2.83 () | .01 | | Weight gain since the age of 20
| | | | | | Range (lbs) | ≤15 | >15 and ≤34 | >34 | | | Cases/Controls | 80/115 | 93/78 | 107/87 | | | Univariate OR (95%
CI) | 1.00 | 1.71 () | 1.67
() | .01 | | Multivariate (95% CI) | | 1.76 () | 1.68 () | .01 | | Weight gain since the age of 30 | | | | | | Range (lbs) | ≤9 | >9 and ≤24 | >24 | | | Cases/Controls | 68/117 | 106/84 | 106/79 | | | Univariate OR (95%
CI) | 1.00 | 2.31 () | 2.17
() | .01 | | Multivariate (95% CI) | | 2.25
() | 1.96 () | .01 | | Weight gain since the age of 40 | | | | | | Range (lbs) | ≤1 | >1 and ≤12 | >12 | | | Cases/Controls | 55/120 | 80/63 | 103/60 | | | Univariate OR (95%
CI) | 1.00 | 1.95 () | 1.99
() | .01 | | Multivariate (95% CI) | | 1.82 () | 1.91 () | .01 |
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at interview.
for age,
education, physical activity, smoking, alcohol consumption and total energy
intake.
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