Journal of Cancer Epidemiology / 2013 / Article / Tab 2

Research Article

Cancer Incidence and Mortality in a Cohort of US Blood Donors: A 20-Year Study

Table 2

Standardized incidence ratio (SIR) for all cancers, allogeneic blood donors with more than one year of followup, Blood Centers of the Pacific, 1991–2009 ( = 54,982).

Age groupNumber of donorsPerson-yearsObservedExpectedSIR95% CI

Males
 18–296,38297,018.39540.92.321.882.84
 30–398,077122,190.7223105.72.111.842.41
 40–497,497111,655.3575236.72.432.232.64
 50–593,99255,664.0737404.71.821.691.96
 60–691,79422,632.8528436.31.211.111.32
 70+3493,928102121.20.840.691.02
 Males total28,091413,088.82,2601,345.51.681.611.75
Females
 18–297,546112,935.316057.42.792.373.26
 30–397,894118,319.1346162.32.131.912.37
 40–496,60997,661.8561336.51.671.531.81
 50–593,27545,759.0444314.51.411.281.55
 60–691,35618,481.9275226.51.211.071.37
 70+2112,6094646.01.000.731.33
 Females total26,891395,766.11,8321,143.21.601.531.68
Total54,982808,854.94,0922,488.71.641.591.70

Person-years of followup: from date of first repository donation to cancer diagnosis, death or Dec. 31, 2009.
SIR: observed/expected.
Expected: SEER age-adjusted and sex- and age-specific incidence rate × person-years of followup.
Age-adjusted incidence rates: SEER age-adjusted rates for malignant cases, years of diagnosis 1992–2009.
Standard population: US 2000 population.