Non-Small-Cell Lung Cancer Clinicopathologic Features and Survival Outcomes in Asian Pacific Islanders Residing in the United States: A SEER Analysis

Table 1

Baseline demographic and clinicopathologic of the study cohort.

Characteristics	NHW (145464)		Hispanic (10350)		Black (22525)		API (11525)
		%		%		%		%
Grade ( < 0.01)
Grade I	8027	5	632	5.4^*	817	3.3^*	724	5.7^*
Grade II	26678	16.5	1849	15.7	3665	14.8^*	2106	16.6
Grade III	44361	27.5	3158	26.8	6968	28.2	3250	25.7^*
Grade IV	3590	2.2	258	2.2	554	2.2	233	1.8^*
Unknown	78658	48.8	5871	49.9^*	12710	51.4^*	6355	50.2^*
AJCC stage 7 ( < 0.01)
Stage I	28649	17.8	1588	13.5^*	3062	12.4^*	1815	14.3
Stage II	21121	13.1	1345	11.4^*	3150	12.7^*	1481	11.7^*
Stage IIIa	22119	13.7	1468	12.5^*	3711	15.0^*	1514	12.0^*
Stage IIIb	4830	3	330	2.8	899	3.6^*	469	3.7^*
Stage IV	68745	42.6	5619	47.7^*	11703	47.4^*	6246	49.3^*
Histology ( < 0.01)
Squamous cell/transitional cell carcinoma	38005	23.6	2265	19.2^*	5955	24.1	1999	15.8^*
Adenocarcinoma in situ AIS	6678	4.1	587	5.0^*	686	2.8^*	794	6.3^*
Nonadenocarcinoma in situ non-AIS	61860	38.3	4931	41.9^*	9512	38.5	6282	49.6^*
Large cell carcinoma	5483	3.4	356	3.0^*	1013	4.1^*	315	2.5^*
Others	49288	30.6	3629	30.8^*	7548	30.5	3278	25.9^*
Age
Mean ± standard deviation	68.86 ± 11.239		67.40 ± 12.395^*		64.65 ± 11.467^*		68.05 ± 12.315^*
Median (range)	70 (15–99)		69 (15–99)		65 (15–99)		69 (20–99)
Age grouping ( < 0.01)
<30	203	0.1	73	0.6^*	41	0.2	34	0.3^*
30–39	815	0.5	170	1.4^*	192	0.8^*	192	1.5^*
40–49	7353	4.6	761	6.5^*	2022	8.2^*	707	5.6^*
50–59	24812	15.4	1924	16.3^*	6279	25.4^*	2210	17.4^*
60–69	47243	29.3	3253	27.6^*	7734	31.3^*	3278	25.9^*
70–79	51282	31.8	3640	30.9	5806	23.5^*	3910	30.9^*
80+	29606	18.4	1947	16.5^*	2640	10.7^*	2337	18.4
Gender ( < 0.01)
Male	85908	53.3	6407	54.4^*	14086	57.0^*	7241	57.2^*
Female	75406	46.7	5361	45.6^*	10628	43.0^*	5427	42.8^*
Birth country ( < 0.01)
United States	108817	67.5	3816	32.4^*	18836	76.2^*	2190	17.3^*
Outside the United States	6565	4.1	4106	34.9^*	376	1.5^*	7369	58.2^*
Unknown	45932	28.5	3846	32.7^*	5502	22.3^*	3109	24.5^*
Marital status ( < 0.01)
Single	16835	10.4	1815	15.4^*	7212	29.2^*	1200	9.5^*
Married	85907	53.3	6074	51.6	8299	33.6^*	8216	64.9^*
Others	53186	33	3452	29.3^*	8136	32.9	2851	22.5^*
Unknown	5386	3.3	427	3.6^*	1067	4.3^*	400	3.2
Tumor size ( < 0.01)
No tumor found	713	0.4	55	0.5	74	0.3^*	45	0.4
≤30 mm	49950	31	3147	26.7^*	6205	25.1^*	3528	27.8^*
>30 mm and ≤50 mm	36401	22.6	2470	21.0^*	5449	22.0^*	3008	23.7^*
>50 mm and ≤70 mm	19615	12.2	1461	12.4	3399	13.8^*	1577	12.4
>70	14848	9.2	1160	9.9^*	3060	12.4^*	1122	8.9
Unknown	393787	24.7	3475	29.5^*	6527	26.4^*	3388	26.7^*

< 0.05 using test when c/w NHW.
Ca.: carcinoma; : frequency; : value; %, percentage; mm: millimeter; API: Asian Pacific Islanders; NHW: non-Hispanic whites.