Promoter Methylation and mRNA Expression of Response Gene to Complement 32 in Breast Carcinoma

Table 2

Promoter methylation frequency of RGC32 gene in breast cancerous and breast normal tissues.

RGC32; methylation status	Normal tissues	Breast tumors	OR (95% CI)	value
UU (%)	55 (87.3)	49 (77.8)	Ref.	—
UM (%)	8 (12.7)	11 (17.5)	1.54 (0.58–4.15)	0.390
MM (%)	0 (0)	3 (4.8)	(0.001)	0.999
Methylation
Absent	118 (93.6)	109 (86.5)	Ref.	—
Present	8 (6.4)	17 (13.5)	2.30 (0.95–5.54)	0.090

UU: fully unmethylated promoter; UM: semimethylated promoter; MM: fully methylated promoter.