Research Article

Role of Pretreatment Hemoglobin-to-Platelet Ratio in Predicting Survival Outcome of Locally Advanced Nasopharyngeal Carcinoma Patients

Table 2

Comparison of baseline characteristics across the HPR groups.

Variable () ()

Age group, (%)
  ≥6023 (15.44)12 (8.57)
  <60126 (84.56)128 (91.43)
Gender, (%)
 Male117 (78.52)87 (62.14)
 Female32 (21.48)53 (37.86)
BMI (kg/m2 median, min-max)23.04 (13.67-37.47)21.39 (13.34-35.34)
Weight loss, (%)
 0-5 kg127 (85.23)94 (67.14)
 5-10 kg13 (8.72)30 (21.43)
  >10 kg9 (6.04)16 (11.43)
Smoking history, (%)
 Yes76 (51.01)62 (44.29)
 No73 (48.99)78 (55.71)
ECOG performance scale, (%)
 025 (16.78)15 (10.71)
 1122 (81.88)116 (82.86)
 22 (1.34)9 (6.43)
WHO histopathologic grade, (%)
 11 (0.67)1 (0.71)
 27 (4.7)7 (5)
 2-36 (4.03)3 (2.14)
 3133 (89.26)128 (91.43)
 Unknown2 (1.34)1 (0.71)
Clinical stage, (%)
 III30 (20.13)15 (10.71)
 IVA78 (52.35)78 (55.71)
 IVB41 (27.52)47 (33.58)
T, (%)
 T1-T345 (30.2)74 (25.61)
 T4104 (69.8)215 (74.39)
N, (%)
 N0-N140 (26.85)29 (20.71)
 N2-N3109 (73.15)111 (79.29)
Therapy, (%)
 CCRT110 (73.83)91 (65)
 NAC+CCRT35 (23.49)47 (33.57)
 RT4 (2.68)2 (1.43)
RT cycle, fraction (median, min-max)34.46 (33-39)34.23 (15-39)
Total dose (Gy (median, min-max))69.69 (66-78)68.73 (30-78)
Overall time (days (median, min-max))54.68 (40-91)56.41(23-97)
Chemosensitizer, (%)
  <5 cycles54 (36.24)50 (35.71)
  ≥5 cycles95 (63.76)90 (64.29)
RT technique, (%)
 2D/3DRCT85 (57.05)83 (59.29)
 2D/3DRCT+IMRT8 (5.37)6 (4.29)
 IMRT56 (37.58)51 (36.42)
Transfusion on CCRT, (%)
 Yes49 (32.89)75 (53.57)
 No100 (67.11)65 (46.43)
Follow up duration (days (median, min-max))822 (65-1095)760 (27-1095)

Note: 2D: two dimensional; 3D-CRT: three-dimensional-conformal radiotherapy; BMI: body mass index; CCRT: concurrent chemoradiotherapy; ECOG: Eastern Cooperative Oncology Group; IMRT: intensity-modulated radiotherapy; NAC: neoadjuvant chemotherapy; RT: radiotherapy; WHO: World Health Organization.