The Front Line of Genomic Translation
1Cancer Control Program, Georgetown Lombardi Comprehensive Cancer Center, Washington, DC 20057, USA
2Social and Behavioral Research Branch, National Human Genome Research Institute, Bethesda, MD 20892-2152, USA
3Department of Psychology, University of Colorado, CO, USA
4Applied Research Program, National Cancer Institute, Bethesda, MD 20892-8322, USA
The Front Line of Genomic Translation
Description
The promise of genomics to inform personalized prevention recommendations and treatments is now being realized in the area of cancer. At one end of the cancer continuum, presymptomatic risk assessments are being used to motivate behavioral risk reduction, screening schedules, and prophylactic prevention for high-risk families. At the other end of the continuum, genetic-based tumor profiling is being used to guide treatment decisions and inform targeted cancer therapies. Yet the utility of these innovations for prevention, early detection, and control of cancer will be heavily influenced by the public's, patients', and healthcare providers' cognitive, emotional, and behavioral responses to these new interventions and other contextual factors.
We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to translate genomic discovery to reduce the burden of cancer. Potential topics include, but are not limited to:
- Recent developments in applying genomics tools towards interventions to improve health behaviors
- Factors influencing screening among high-risk families
- Challenges in developing risk algorithms to stratify patients/populations into risk categories
- Progress in using genomics to identify intermediate (epigenetic) markers of intervention benefit
- Programs to assist patients in understanding and making decisions about genomics-based treatment recommendations
- Health disparities in access to genomics-informed cancer prevention, screening, and treatment options
Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jce/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: