Journal of Chemistry

Journal of Chemistry / 2005 / Article

Open Access

Volume 2 |Article ID 370478 | https://doi.org/10.1155/2005/370478

L. D. Srinivas, P. Ravi Kumar, B. S. Sastry, "Ion Association Methods for the Determination of Fexofenadine in Pharmaceutical Preparations", Journal of Chemistry, vol. 2, Article ID 370478, 4 pages, 2005. https://doi.org/10.1155/2005/370478

Ion Association Methods for the Determination of Fexofenadine in Pharmaceutical Preparations

Received10 May 2005
Accepted31 May 2005

Abstract

Two simple and sensitive Visible spectrophotometric methods (A and B) for the determination of Fexofenadine (FEX) in bulk sample and pharmaceutical formulations are described. Methods A and B are based on the formation of ion-association complex involving carboxylic acid group of FEX and the basic dyes, Safranin-O (SFN-O, method A), methylene blue (MB, method B). The results obtained in the above two methods are reproducible and are statistically validated and found to be suitable for the assay of Fexofenadine in bulk and its pharmaceutical formulations.

Copyright © 2005 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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