Journal of Chemistry

Journal of Chemistry / 2006 / Article

Open Access

Volume 3 |Article ID 186294 | https://doi.org/10.1155/2006/186294

K. H. Patel, A. G. Mehta, "Synthesis and Antifungal Activity of Azetidinone and Thiazolidinones Derivatives of 2-Amino-6-(2-naphthalenyl)thiazolo[3,2-d]thiadiazole", Journal of Chemistry, vol. 3, Article ID 186294, 7 pages, 2006. https://doi.org/10.1155/2006/186294

Synthesis and Antifungal Activity of Azetidinone and Thiazolidinones Derivatives of 2-Amino-6-(2-naphthalenyl)thiazolo[3,2-d]thiadiazole

Received07 Jul 2006
Accepted22 Aug 2006

Abstract

2-Amino-6-(2-naphthalenyl)thiazolo[3,2-d]thiadiazole [1] was prepared by treatment of KCNS and Br2 on 2-Amino-4-(2-naphthalenyl) thiazole. This amine on facile condensation with aromatic aldehydes afford Schiff Base/anils/azomethines(2a-h). These anils on cyclocondensation reaction with chloro acetyl chloride and thio glycolic acid (i.e. mercapto acetic acid) afford 2-azetidinones and 4-thiazolidinones respectively. The prepared compounds have been screened on some stains of fungai.

Copyright © 2006 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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