Synthesis, Characterization and Biological Activities of Cu(II), Co(II), Ni(II), Mn(II) and Fe(III) Complexes with Schiff Base Derived from 3-(4-Chlorophenoxymethyl)-4-amino-5-mercapto-1,2,4-triazole

Abstract

Coordination complexes of Cu(II),Co(II), Ni(II), Mn(II) and Fe(III)with Schiff bases derived from 3-(4-chlorophenoxymethyl)-4-amino-5-mercapto-1, 2, 4-triazole and substituted aldehydes have been synthesized. The complexes were characterized by elemental analysis, conductivity measurements, magnetic susceptibility data, electronic, IR, ESR and ¹H NMR spectral data. On the basis spectroscopic studies, the Schiff base is monobasic bidentate ligand having the composition ML₂(2H₂O) Where M = Cu(II), Co(II), Ni(II) ,Mn(II), ML₂(H₂O)Cl Where M = Fe(III). Various physicochemical data suggest a six coordinated octahedral geometry for Cu(II),Co(II), Ni(II), Mn(II) and Fe(III) complexes. The antibacterial activities of ligand and its complexes were screened by cup plate method.