Microwave Induced Synthesis and Anti bacterial Activity of Some 6-(2-Hyroxy phenyl)-4-(substituted phenyl) -3-oxo-2, 3, 4, 5- tetrahydro-1H-indazoles

Abstract

The title compounds were synthesized by condensation of 2-hydroxy chalcones with ethylacetoacetate to get intermediate 3,5-diaryl-6-carbethoxy-2-cyclohexenone which were subsequently treated with hydrazine hydrate to afford the title compounds. All the transformation was carried out under microwave induced conditions. The synthesized compounds were screened for their antibacterial activity in vitro.