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E-Journal of Chemistry
Volume 6, Issue 3, Pages 775-779
http://dx.doi.org/10.1155/2009/404596

Synthesis and Antimicrobial Activity ofSome New 2-Substituted Benzothiazole Derivatives

B. Rajeeva, N. Srinivasulu, and S. M. Shantakumar

Department of Pharmaceutical Chemistry, V. L. College of Pharmacy, Raichur-584103, Karnataka, India

Received 8 January 2009; Accepted 10 March 2009

Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Some new 2-(5-substituted-1,3,4-oxadiazole-2-yl)-1,3- benzothiazole (3a-j) were synthesized by refluxing benzothiazolyl carboxyhydrazide with different aryl acids in phosphoryl chloride. Structures of the synthesized compounds were established on the basis of 1H NMR and Mass spectral data. The anti microbial activity of the synthesized compounds was evaluated by disc diffusion method.